The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications
Immunotherapy has revolutionized cancer treatment and rejuvenated the field of tumor
immunology. Several types of immunotherapy, including adoptive cell transfer (ACT) and …
immunology. Several types of immunotherapy, including adoptive cell transfer (ACT) and …
Cancer immunotherapies: advances and bottlenecks
R Rui, L Zhou, S He - Frontiers in Immunology, 2023 - frontiersin.org
Immunotherapy has ushered in a new era in cancer treatment, and cancer immunotherapy
continues to be rejuvenated. The clinical goal of cancer immunotherapy is to prime host …
continues to be rejuvenated. The clinical goal of cancer immunotherapy is to prime host …
Immunosuppressive tumor microenvironment modulation by chemotherapies and targeted therapies to enhance immunotherapy effectiveness
R Barnestein, L Galland, L Kalfeist, F Ghiringhelli… - …, 2022 - Taylor & Francis
With the rapid clinical development of immune checkpoint inhibitors (ICIs), the standard of
care in cancer management has evolved rapidly. However, immunotherapy is not currently …
care in cancer management has evolved rapidly. However, immunotherapy is not currently …
Targeted anti‐tumor immunotherapy using tumor infiltrating cells
In the tumor microenvironment, T cells, B cells, and many other cells play important and
distinct roles in anti‐tumor immunotherapy. Although the immune checkpoint blockade and …
distinct roles in anti‐tumor immunotherapy. Although the immune checkpoint blockade and …
Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling
KB Nguyen, S Spranger - Journal of Cell Biology, 2019 - rupress.org
The development of cancer immunotherapies has been guided by advances in our
understanding of the dynamics between tumor cells and immune populations. An emerging …
understanding of the dynamics between tumor cells and immune populations. An emerging …
The influence of microenvironment on tumor immunotherapy
J Zhang, Z Shi, X Xu, Z Yu, J Mi - The FEBS journal, 2019 - Wiley Online Library
Tumor immunotherapy has achieved remarkable efficacy, with immune‐checkpoint
inhibitors as especially promising candidates for cancer therapy. However, some issues …
inhibitors as especially promising candidates for cancer therapy. However, some issues …
Immuno-oncology-101: overview of major concepts and translational perspectives
Cancer immunotherapy is demonstrating impressive clinical benefit in different malignancies
and clinical oncologists are increasingly turning their attention to immune-oncology. It is now …
and clinical oncologists are increasingly turning their attention to immune-oncology. It is now …
Recent advances and challenges in cancer immunotherapy
C Peterson, N Denlinger, Y Yang - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy helps a person's immune system to target tumor cells.
Recent advances in cancer immunotherapy, including immune checkpoint inhibition …
Recent advances in cancer immunotherapy, including immune checkpoint inhibition …
Immune suppressive mechanisms in the tumor microenvironment
DH Munn, V Bronte - Current opinion in immunology, 2016 - Elsevier
Highlights•Tumors exaggerate and exploit natural immunosuppressive and tolerogenic
mechanisms.•This milieu favors angiogenesis and tissue remodeling but is suppressive for T …
mechanisms.•This milieu favors angiogenesis and tissue remodeling but is suppressive for T …
The immune landscape of human tumors: Implications for cancer immunotherapy
G Bindea, B Mlecnik, HK Angell, J Galon - Oncoimmunology, 2014 - Taylor & Francis
Understanding the spontaneous immune response of cancer patients is critical for the
design of efficient anticancer immunotherapies. The power of integrative tumor immunology …
design of efficient anticancer immunotherapies. The power of integrative tumor immunology …