microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7

JF Chen, Y Tao, J Li, Z Deng, Z Yan, X Xiao… - Journal of Cell …, 2010 - rupress.org
Skeletal muscle satellite cells are adult stem cells responsible for postnatal skeletal muscle
growth and regeneration. Paired-box transcription factor Pax7 plays a central role in satellite …

Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination

HC Olguin, Z Yang, SJ Tapscott, BB Olwin - The Journal of cell biology, 2007 - rupress.org
Postnatal growth and regeneration of skeletal muscle requires a population of resident
myogenic precursors named satellite cells. The transcription factor Pax7 is critical for …

Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex

IW McKinnell, J Ishibashi, F Le Grand, VGJ Punch… - Nature cell …, 2008 - nature.com
Satellite cells purified from adult skeletal muscle can participate extensively in muscle
regeneration and can also re-populate the satellite cell pool, suggesting that they have …

Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression

CG Crist, D Montarras… - Proceedings of the …, 2009 - National Acad Sciences
Skeletal muscle stem cells are regulated by Pax3/7. During development, Pax3 is required
for the maintenance of these cells in the somite and their migration to sites of myogenesis; …

miR-206 and-486 induce myoblast differentiation by downregulating Pax7

BK Dey, J Gagan, A Dutta - Molecular and cellular biology, 2011 - Taylor & Francis
The Pax7 transcription factor is required for muscle satellite cell biogenesis and specification
of the myogenic precursor lineage. Pax7 is expressed in proliferating myoblasts but is …

Alternative polyadenylation mediates microRNA regulation of muscle stem cell function

SC Boutet, TH Cheung, NL Quach, L Liu, SL Prescott… - Cell stem cell, 2012 - cell.com
Pax3, a key myogenic regulator, is transiently expressed during activation of adult muscle
stem cells, or satellite cells (SCs), and is also expressed in a subset of quiescent SCs …

Pax7 and myogenic progression in skeletal muscle satellite cells

PS Zammit, F Relaix, Y Nagata, AP Ruiz… - Journal of cell …, 2006 - journals.biologists.com
Skeletal muscle growth and regeneration are attributed to satellite cells-muscle stem cells
resident beneath the basal lamina that surrounds each myofibre. Quiescent satellite cells …

Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells

SA Dick, NC Chang, NA Dumont… - Proceedings of the …, 2015 - National Acad Sciences
Compensatory growth and regeneration of skeletal muscle is dependent on the resident
stem cell population, satellite cells (SCs). Self-renewal and maintenance of the SC niche is …

Satellite cells, the engines of muscle repair

YX Wang, MA Rudnicki - Nature reviews Molecular cell biology, 2012 - nature.com
Satellite cells are a heterogeneous population of stem and progenitor cells that are required
for the growth, maintenance and regeneration of skeletal muscle. The transcription factors …

Muscle-specific microRNA miR-206 promotes muscle differentiation

HK Kim, YS Lee, U Sivaprasad, A Malhotra… - The Journal of cell …, 2006 - rupress.org
Three muscle-specific microRNAs, miR-206,-1, and-133, are induced during differentiation
of C2C12 myoblasts in vitro. Transfection of miR-206 promotes differentiation despite the …