microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7
JF Chen, Y Tao, J Li, Z Deng, Z Yan, X Xiao… - Journal of Cell …, 2010 - rupress.org
Skeletal muscle satellite cells are adult stem cells responsible for postnatal skeletal muscle
growth and regeneration. Paired-box transcription factor Pax7 plays a central role in satellite …
growth and regeneration. Paired-box transcription factor Pax7 plays a central role in satellite …
Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination
HC Olguin, Z Yang, SJ Tapscott, BB Olwin - The Journal of cell biology, 2007 - rupress.org
Postnatal growth and regeneration of skeletal muscle requires a population of resident
myogenic precursors named satellite cells. The transcription factor Pax7 is critical for …
myogenic precursors named satellite cells. The transcription factor Pax7 is critical for …
Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex
IW McKinnell, J Ishibashi, F Le Grand, VGJ Punch… - Nature cell …, 2008 - nature.com
Satellite cells purified from adult skeletal muscle can participate extensively in muscle
regeneration and can also re-populate the satellite cell pool, suggesting that they have …
regeneration and can also re-populate the satellite cell pool, suggesting that they have …
Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression
CG Crist, D Montarras… - Proceedings of the …, 2009 - National Acad Sciences
Skeletal muscle stem cells are regulated by Pax3/7. During development, Pax3 is required
for the maintenance of these cells in the somite and their migration to sites of myogenesis; …
for the maintenance of these cells in the somite and their migration to sites of myogenesis; …
miR-206 and-486 induce myoblast differentiation by downregulating Pax7
The Pax7 transcription factor is required for muscle satellite cell biogenesis and specification
of the myogenic precursor lineage. Pax7 is expressed in proliferating myoblasts but is …
of the myogenic precursor lineage. Pax7 is expressed in proliferating myoblasts but is …
Alternative polyadenylation mediates microRNA regulation of muscle stem cell function
Pax3, a key myogenic regulator, is transiently expressed during activation of adult muscle
stem cells, or satellite cells (SCs), and is also expressed in a subset of quiescent SCs …
stem cells, or satellite cells (SCs), and is also expressed in a subset of quiescent SCs …
Pax7 and myogenic progression in skeletal muscle satellite cells
PS Zammit, F Relaix, Y Nagata, AP Ruiz… - Journal of cell …, 2006 - journals.biologists.com
Skeletal muscle growth and regeneration are attributed to satellite cells-muscle stem cells
resident beneath the basal lamina that surrounds each myofibre. Quiescent satellite cells …
resident beneath the basal lamina that surrounds each myofibre. Quiescent satellite cells …
Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells
Compensatory growth and regeneration of skeletal muscle is dependent on the resident
stem cell population, satellite cells (SCs). Self-renewal and maintenance of the SC niche is …
stem cell population, satellite cells (SCs). Self-renewal and maintenance of the SC niche is …
Satellite cells, the engines of muscle repair
YX Wang, MA Rudnicki - Nature reviews Molecular cell biology, 2012 - nature.com
Satellite cells are a heterogeneous population of stem and progenitor cells that are required
for the growth, maintenance and regeneration of skeletal muscle. The transcription factors …
for the growth, maintenance and regeneration of skeletal muscle. The transcription factors …
Muscle-specific microRNA miR-206 promotes muscle differentiation
Three muscle-specific microRNAs, miR-206,-1, and-133, are induced during differentiation
of C2C12 myoblasts in vitro. Transfection of miR-206 promotes differentiation despite the …
of C2C12 myoblasts in vitro. Transfection of miR-206 promotes differentiation despite the …