In recent decades, the Fontan procedure and its variations have resulted in markedly
improved outcomes of patients with single-ventricle physiology. These improvements are …

The Fontan circulation is a palliative concept for patients with univentricular hearts. The
central veins are connected directly to the pulmonary arteries (cavo-pulmonary connection) …

No previous meta-analysis has evaluated the efficacy and safety of pulmonary vasodilators
in Fontan physiology. Recent relative trials have obtained conflicting results regarding …

The Fontan operation is the final step of palliation for patients with a functionally single
ventricle. Since its introduction in the 1970s, the Fontan surgery has become part of a …

Background The Fontan circulation is a successful operative strategy for abolishing cyanosis
and chronic volume overload in patients with congenital heart disease with single ventricle …

With great interest we read the recent article by Wang et al. in Pulmonary Circulation
presenting a meta-analysis on the efficacy and safety of pulmonary vasodilator therapy in …

Summary Introduction The Fontan procedure is the palliative procedure for single ventricle
physiology. Pulmonary resistance plays a key role in the success of this operation. There are …

We aimed to assess the efficacy and safety of pulmonary vasodilators in patients after the
Fontan procedure. The PubMed, EMBASE, and Cochrane Library databases were searched …

In single ventricle patients, the Fontan palliation separates the pulmonary and systemic
circulation, eliminating cyanosis and reducing volume load to the systemic ventricle. The …

Background Nonpulsatile pulmonary blood flow in Fontan circulation results in pulmonary
vascular disease, but the potential relationships between pulmonary vascular resistance …