Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus

D Ferguson, BN Finck - Nature Reviews Endocrinology, 2021 - nature.com
Non-alcoholic fatty liver disease (NAFLD) has emerged as the most prevalent liver disease
in the world, yet there are still no approved pharmacological therapies to prevent or treat this …

Treatments for NAFLD: state of art

A Mantovani, A Dalbeni - International journal of molecular sciences, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is to date the most common chronic liver disease
in clinical practice and, consequently, a major health problem worldwide. It affects …

Advancements in the treatment of non-alcoholic fatty liver disease (NAFLD)

L Rong, J Zou, W Ran, X Qi, Y Chen, H Cui… - Frontiers in …, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a series of diseases, involving excessive lipid
deposition in the liver and is often accompanied by obesity, diabetes, dyslipidemia …

Treatment of patients with type 2 diabetes and non-alcoholic fatty liver disease: current approaches and future directions

K Cusi - Diabetologia, 2016 - Springer
Non-alcoholic fatty liver disease (NAFLD) is reaching epidemic proportions in patients with
type 2 diabetes. Patients with NAFLD are at increased risk of more aggressive liver disease …

Targeting metabolism, insulin resistance, and diabetes to treat nonalcoholic steatohepatitis

BN Finck - Diabetes, 2018 - Am Diabetes Assoc
Obesity, insulin resistance, and diabetes are strongly linked to the accumulation of
excessive lipids in the liver parenchyma, a condition known as nonalcoholic fatty liver …

New therapeutic strategies in nonalcoholic fatty liver disease: A focus on promising drugs for nonalcoholic steatohepatitis

N Pydyn, K Miękus, J Jura, J Kotlinowski - Pharmacological Reports, 2020 - Springer
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide.
Globally, it is currently the most common liver disease and is estimated to affect up to 25% of …

[HTML][HTML] Current treatment paradigms and emerging therapies for NAFLD/NASH

S Raza, S Rajak, A Upadhyay, A Tewari… - Frontiers in bioscience …, 2021 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is one the fastest emerging manifestations of the
metabolic syndrome worldwide. Non-alcoholic steatohepatitis (NASH), the progressive form …

Towards precision medicine in non-alcoholic fatty liver disease

SM Francque - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) refers to the accumulation of lipid laden
vacuoles in hepatocytes, occurring in the context of visceral adiposity, insulin resistance and …

Advances in the understanding and treatment of nonalcoholic fatty liver disease

SA Harrison, AM Di Bisceglie - Drugs, 2003 - Springer
Nonalcoholic fatty liver disease (NAFLD) is a well recognised form of chronic liver disease
that has recently gained greater recognition. Originally described in the late 1950s, NAFLD …

The challenge of developing novel pharmacological therapies for non‐alcoholic steatohepatitis

D Schuppan, MD Gorrell, T Klein, M Mark… - Liver …, 2010 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) is an umbrella term for a series of hepatic
pathologies that begin with relatively benign steatosis and can, with appropriate triggers …