A two-component regulatory system impacts extracellular membrane-derived vesicle production in group A Streptococcus

U Resch, JA Tsatsaronis, A Le Rhun, G Stübiger… - MBio, 2016 - Am Soc Microbiol
Export of macromolecules via extracellular membrane-derived vesicles (MVs) plays an
important role in the biology of Gram-negative bacteria. Gram-positive bacteria have also …

Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae

A Olaya-Abril, R Prados-Rosales, MJ McConnell… - Journal of …, 2014 - Elsevier
Extracellular vesicles are produced by many pathogenic microorganisms and have varied
functions that include secretion and release of microbial factors, which contribute to …

Extracellular vesicle biogenesis and functions in gram-positive bacteria

P Briaud, RK Carroll - Infection and immunity, 2020 - Am Soc Microbiol
Extracellular vesicles (EVs) are membrane-derived lipid bilayers secreted by bacteria and
eukaryotic cells. Bacterial membrane vesicles were discovered over 60 years ago and have …

Gram‐positive bacteria produce membrane vesicles: Proteomics‐based characterization of Staphylococcus aureus‐derived membrane vesicles

EY Lee, DY Choi, DK Kim, JW Kim, JO Park, S Kim… - …, 2009 - Wiley Online Library
Although archaea, Gram‐negative bacteria, and mammalian cells constitutively secrete
membrane vesicles (MVs) as a mechanism for cell‐free intercellular communication, this …

Envelope control of outer membrane vesicle production in Gram-negative bacteria

C Schwechheimer, CJ Sullivan, MJ Kuehn - Biochemistry, 2013 - ACS Publications
All Gram-negative bacteria studied to date have been shown to produce outer membrane
vesicles (OMVs), which are budded, released spheres of outer membrane with periplasmic …

Streptococcal extracellular membrane vesicles are rapidly internalized by immune cells and alter their cytokine release

M Mehanny, M Koch, CM Lehr… - Frontiers in immunology, 2020 - frontiersin.org
Extracellular vesicles are membranous structures shed by almost every living cell. Bacterial
gram-negative outer membrane vesicles (OMVs) and gram-positive membrane vesicles …

Bacterial outer membrane vesicles and the host–pathogen interaction

MJ Kuehn, NC Kesty - Genes & development, 2005 - genesdev.cshlp.org
Extracellular secretion of products is the major mechanism by which Gram-negative
pathogens communicate with and intoxicate host cells. Vesicles released from the envelope …

Virulence and immunomodulatory roles of bacterial outer membrane vesicles

TN Ellis, MJ Kuehn - Microbiology and molecular biology reviews, 2010 - Am Soc Microbiol
Outer membrane (OM) vesicles are ubiquitously produced by Gram-negative bacteria during
all stages of bacterial growth. OM vesicles are naturally secreted by both pathogenic and …

Staphylococcus aureus Produces Membrane-Derived Vesicles That Induce Host Cell Death

M Gurung, DC Moon, CW Choi, JH Lee, YC Bae, J Kim… - PloS one, 2011 - journals.plos.org
Gram-negative bacteria produce outer membrane vesicles that play a role in the delivery of
virulence factors to host cells. However, little is known about the membrane-derived vesicles …

Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi

L Brown, JM Wolf, R Prados-Rosales… - Nature Reviews …, 2015 - nature.com
Extracellular vesicles (EVs) are produced by all domains of life. In Gram-negative bacteria,
EVs are produced by the pinching off of the outer membrane; however, how EVs escape the …