Hereditary transthyretin amyloidosis (ATTRv) is a rare, progressive, and life-threatening
disease caused by misfolded transthyretin (TTR) proteins that aggregate as abnormal …

Hereditary transthyretin amyloidosis (ATTRv) is a rare, progressive, and life-threatening
disease caused by misfolded transthyretin (TTR) proteins that aggregate as abnormal …

ABSTRACT Background Hereditary transthyretin amyloidosis (ATTRv) is a disabling and life-
threatening disease that primarily affects the nervous system and heart. Its kidney …

The amyloidoses are protein-misfolding disorders associated with progressive organ
dysfunction. Immunoglobulin light chain is the most common, amyloid A the longest …

Background Cardiac and neurological involvements are the main clinical features of
hereditary transthyretin (ATTRv) amyloidosis. Few data are available about ATTRv amyloid …

Background Hereditary transthyretin V30M (ATTR) amyloidosis (ATTR p. Val50Met) is a
disease with varied phenotypes, although the identifying signs are neuropathy and …

Hereditary amyloidogenic transthyretin (ATTRv) amyloidosis is a rare autosomal dominantly
inherited disorder caused by mutations in the transthyretin (TTR) gene. The pathogenetic …

We have read with great interest the results of the article by Bleyer et al.[1] showing that a
broad panel genetic testing with 382 genes associated with kidney disease identified a …

Amyloidoses represent a group of diseases characterized by the pathological accumulation
in the extracellular area of insoluble misfolded protein material called “amyloid”. The …

Background Tafamidis delayed neuropathic progression in patients with transthyretin
amyloidosis [Citation 1], but long-term effectiveness in multisystem commitment is unclear. In …