[HTML][HTML] Astaxanthin alleviates aflatoxin B1-induced oxidative stress and apoptosis in IPEC-J2 cells via the Nrf2 signaling pathway

Y Tian, H Che, J Yang, Y Jin, H Yu, C Wang, Y Fu, N Li… - Toxins, 2023 - mdpi.com
Aflatoxin B1 (AFB1), a typical fungal toxin found in feed, is highly carcinogenic. Oxidative
stress is one of the main ways it exerts its toxicity; therefore, finding a suitable antioxidant is …

Aflatoxin G1-induced oxidative stress causes DNA damage and triggers apoptosis through MAPK signaling pathway in A549 cells

H Shen, J Liu, Y Wang, H Lian, J Wang, L Xing… - Food and chemical …, 2013 - Elsevier
Our previous studies showed that Aflatoxin G 1 (AFG 1) could induce lung adenocarcinoma,
and that the cancer cells originated from alveolar type II cells (AT-II cells). Recently, we …

[HTML][HTML] Chlorogenic acid alleviated AFB1-induced hepatotoxicity by regulating mitochondrial function, activating Nrf2/HO-1, and inhibiting noncanonical NF-κB …

Q Wang, T Liu, M Koci, Y Wang, Y Fu, M Ma, Q Ma… - Antioxidants, 2023 - mdpi.com
Aflatoxin B1 (AFB1), a kind of mycotoxin, imposes acute or chronic toxicity on humans and
causes great public health concerns. Chlorogenic acid (CGA), a natural phenolic substance …

Therapeutic detoxification of quercetin for aflatoxin B1-related toxicity: Roles of oxidative stress, inflammation, and metabolic enzymes

C Dai, G Sharma, G Liu, J Shen, B Shao, Z Hao - Environmental Pollution, 2024 - Elsevier
Aflatoxins (AFTs), a type of mycotoxin mainly produced by Aspergillus parasiticus and
Aspergillus flavus, could be detected in food, feed, Chinese herbal medicine, grain crops …

Aflatoxin B1-induced toxicity in HepG2 cells inhibited by carotenoids: morphology, apoptosis and DNA damage

L Reddy, B Odhav, K Bhoola - 2006 - degruyter.com
Abstract Aflatoxin B1 (AFB1) is a fungal toxin that has been associated with primary
hepatocellular carcinoma (HCC) in humans. This study was undertaken to determine the …

[HTML][HTML] Evaluation of neuroprotective effects of quercetin against aflatoxin B1-intoxicated mice

E Gugliandolo, AF Peritore, R D'Amico, P Licata… - Animals, 2020 - mdpi.com
Simple Summary Aflatoxin B1 (AFB1) is a mycotoxin commonly present in feed,
characterized by several toxic effects. AFB1 has been described as being responsible for …

Caffeic acid protects against DNA damage, oxidative and inflammatory mediated toxicities, and upregulated caspases activation in the hepatorenal system of rats …

SE Owumi, CE Irozuru, UO Arunsi, AK Oyelere - Toxicon, 2022 - Elsevier
Aflatoxicosis can induce largescale toxicities in predisposed populations. Food fortification
with adequate antioxidant sources may reduce the toxic burden from aflatoxicosis. We …

Mitigating the adverse effects of Aflatoxin B1 in LMH, IPEC-J2 and 3D4/21 cells by a novel integrated agent

YX Mo, ML Ruan, J Wang, Y Liu, YY Wu… - Food and Chemical …, 2023 - Elsevier
This study was to evaluate the efficacy of TOXO-XL (XL), an integrated mycotoxin-mitigating
agent, on aflatoxin B 1 (AFB 1)-induced damage in Leghorn male hepatoma (LMH), porcine …

[HTML][HTML] Combined toxic effects of aflatoxin B2 and the protective role of resveratrol in Swiss albino mice

A Gündüz, E Yalçın, K Çavuşoğlu - Scientific Reports, 2021 - nature.com
In this study, the toxic effects of aflatoxin B2 (AFB2) on Swiss albino mice and the protective
effects of resveratrol were investigated. Physiological (body weight, liver and kidney weight) …

Resveratrol inhibits aflatoxin B1-induced oxidative stress and apoptosis in bovine mammary epithelial cells and is involved the Nrf2 signaling pathway

Y Zhou, Y Jin, H Yu, A Shan, J Shen, C Zhou, Y Zhao… - Toxicon, 2019 - Elsevier
Aflatoxins are widely occurring food contaminants that are particularly harmful to dairy
products and cows. The plant polyphenol resveratrol has been reported to have a good …