Rationale: Chronic obstructive pulmonary disease (COPD) is associated with increased
morbidity and mortality from cardiovascular disease. Although a close association between …

Background Numerous population-based studies have suggested that impaired lung
function is associated with subsequent coronary heart diseases–related mortality and …

Rationale: The aim of the ALICE (Airflow Limitation in Cardiac Diseases in Europe) study
was to investigate the prevalence of airflow limitation in patients with ischemic heart disease …

Airflow obstruction is an independent risk factor for cardiovascular events in the general
population. The affected vascular bed and contribution of emphysema to cardiovascular risk …

Rationale: Lower FEV1 is associated with increased prevalence of atherosclerosis;
however, causal mechanisms remain elusive. Objectives: To determine if systemic …

An association between reduced pulmonary function and increased risk of atherosclerotic
vascular events has been reported. The mechanisms underlying this association are …

Rationale: Cardiovascular disease is a major cause of morbidity and mortality in patients
with chronic obstructive pulmonary disease (COPD), which may in part be attributable to …

Introduction: Lung function impairment may be a risk factor for cardiovascular disease (CVD)
events. Objective: To determine the relationship between the severity of airflow obstruction …

Rationale: Impaired vascular reactivity is an important factor in the pathogenesis of
cardiovascular disease. Objectives: We sought to assess vascular reactivity in patients with …

Despite the established role of cigarette smoking in the causation of chronic air-flow
obstruction (CAO), only a small proportion of regular cigarette smokers develop significant …