[HTML][HTML] Dupilumab in inflammatory skin diseases: a systematic review
Dupilumab was first approved for the treatment of atopic dermatitis (AD) and blocks the
signaling of interleukin (IL)-4 and-13. Several other chronic skin conditions share …
signaling of interleukin (IL)-4 and-13. Several other chronic skin conditions share …
Dupilumab in dermatology: potential for uses beyond atopic dermatitis
Dupilumab inhibits the interleukin-4 receptor subunit α and is FDA approved for treatment of
moderate-to-severe atopic dermatitis. It is a relatively new drug, and whether it is efficacious …
moderate-to-severe atopic dermatitis. It is a relatively new drug, and whether it is efficacious …
Dupilumab use in dermatologic conditions beyond atopic dermatitis–a systematic review
AJ Hendricks, G Yosipovitch, VY Shi - Journal of Dermatological …, 2021 - Taylor & Francis
Importance: While dupilumab has emerged as an effective treatment for moderate-to-severe
atopic dermatitis (AD) since its approval in 2017, interleukin-4 and 13 blockade has also …
atopic dermatitis (AD) since its approval in 2017, interleukin-4 and 13 blockade has also …
The emerging role of dupilumab in dermatological indications
M Napolitano, A Di Guida, M Nocerino… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Dupilumab represents a breakthrough in the management of atopic dermatitis
(AD), thanks to its powerful T-helper (Th) 2-mediated immunity modulating activity. It can …
(AD), thanks to its powerful T-helper (Th) 2-mediated immunity modulating activity. It can …
Dupilumab: an evidence-based review of its potential in the treatment of atopic dermatitis
P Eshtiaghi, MJ Gooderham - Core evidence, 2018 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is a recurrent, pruritic inflammatory skin disease with
complex immunopathogenesis characterized by a dominant TH2 response. Dupilumab is an …
complex immunopathogenesis characterized by a dominant TH2 response. Dupilumab is an …
[HTML][HTML] Dupilumab shows long-term safety and efficacy in patients with moderate to severe atopic dermatitis enrolled in a phase 3 open-label extension study
Background Significant unmet need exists for long-term treatment of moderate to severe
atopic dermatitis (AD). Objective To assess the long-term safety and efficacy of dupilumab in …
atopic dermatitis (AD). Objective To assess the long-term safety and efficacy of dupilumab in …
Dupilumab: a review of its use in the treatment of atopic dermatitis
MJ Gooderham, HC Hong, P Eshtiaghi… - Journal of the American …, 2018 - Elsevier
Atopic dermatitis (AD) is a chronic, pruritic immune-mediated inflammatory dermatosis
characterized by a T helper 2 (Th2) immune response phenotype and may be associated …
characterized by a T helper 2 (Th2) immune response phenotype and may be associated …
[HTML][HTML] Dupilumab for atopic dermatitis: the silver bullet we have been searching for?
ATU Din, I Malik, D Arshad, ATU Din - Cureus, 2020 - ncbi.nlm.nih.gov
Atopic dermatitis is a chronic inflammatory condition of the skin affecting a large number of
people worldwide. Historically, this condition has been managed by topical corticosteroids …
people worldwide. Historically, this condition has been managed by topical corticosteroids …
Dupilumab in atopic dermatitis: rationale, latest evidence and place in therapy
LFM Ariëns, DS Bakker… - … advances in chronic …, 2018 - journals.sagepub.com
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases. The
prevalence of AD is increasing and is currently estimated at 10–20% in adults worldwide. In …
prevalence of AD is increasing and is currently estimated at 10–20% in adults worldwide. In …
Treatment with dupilumab in patients with atopic dermatitis: systematic review and meta-analysis
Atopic dermatitis (AD) is a type 2 chronic skin disorder associated with systemic and
psychosocial comorbidities decreasing the quality of life for many patients. Dupilumab, a …
psychosocial comorbidities decreasing the quality of life for many patients. Dupilumab, a …