Exosomes derived from oxLDL-stimulated macrophages induce neutrophil extracellular traps to drive atherosclerosis

YG Zhang, Y Song, XL Guo, RY Miao, YQ Fu, CF Miao… - Cell cycle, 2019 - Taylor & Francis
This study aimed to investigate the role and underlying mechanism of exosomes secreted by
oxidized low-density lipoprotein (oxLDL)-stimulated macrophages in the progression of …

Exosome-encapsulated miR-505 from ox-LDL-treated vascular endothelial cells aggravates atherosclerosis by inducing NET formation

L Chen, L Hu, Q Li, J Ma, H Li - Acta biochimica et biophysica …, 2019 - academic.oup.com
Neutrophil extracellular traps (NETs) play an important role in the pathological process of
atherosclerosis (AS). This study aims to evaluate whether exosomes from oxidized low …

[PDF][PDF] Exosome-mediated miR-106a-3p derived from ox-LDL exposed macrophages accelerated cell proliferation and repressed cell apoptosis of human vascular …

Y Liu, WL Zhang, JJ Gu, YQ Sun, HZ Cui… - European Review for …, 2020 - europeanreview.org
OBJECTIVE: Atherosclerosis (AS) is a leading disease with high mortality and morbidity in
the world. It has been demonstrated that exosomes can transfer some miRNAs or proteins to …

Exosomes derived from mesenchymal stem cells attenuate the progression of atherosclerosis in ApoE−/-mice via miR-let7 mediated infiltration and polarization of M2 …

J Li, H Xue, T Li, X Chu, D Xin, Y Xiong, W Qiu… - Biochemical and …, 2019 - Elsevier
Atherosclerosis is a chronic inflammatory disease of the vasculature. Exosomes derived
from mesenchymal stem cells (MSCs) exert immunomodulatory and immunosuppressive …

Mesenchymal stem cell-derived exosomal miR-21a-5p promotes M2 macrophage polarization and reduces macrophage infiltration to attenuate atherosclerosis

J Ma, L Chen, X Zhu, Q Li, L Hu… - Acta biochimica et …, 2021 - academic.oup.com
Atherosclerosis (AS) is the main pathological basis for ischemic cardiovascular and
cerebrovascular diseases. Mesenchymal stem cell (MSC)-derived exosomes have the …

[HTML][HTML] Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation

J Zhu, B Liu, Z Wang, D Wang, H Ni, L Zhang… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: During the development of atherosclerosis, macrophages secrete exosomes that
regulate vascular smooth muscle cells (VSMCs); however, whether nicotine, a major …

Exosomes: multifaceted messengers in atherosclerosis

H Wang, Y Xie, AM Salvador, Z Zhang, K Chen… - Current Atherosclerosis …, 2020 - Springer
Abstract Purpose of Review Atherosclerosis (AS) is a chronic inflammatory disease that
contributes to the development of coronary artery disease, which has become a leading …

[HTML][HTML] Macrophage exosomes resolve atherosclerosis by regulating hematopoiesis and inflammation via MicroRNA cargo

L Bouchareychas, P Duong, S Covarrubias, E Alsop… - Cell reports, 2020 - cell.com
Developing strategies that promote the resolution of vascular inflammation and
atherosclerosis remains a major therapeutic challenge. Here, we show that exosomes …

Macrophage‐derived exosomal miR‐4532 promotes endothelial cells injury by targeting SP1 and NF‐κB P65 signalling activation

P Liu, S Wang, G Wang, M Zhao, F Du… - Journal of cellular …, 2022 - Wiley Online Library
Atherosclerosis is a complex pathological process involving macrophages, endothelial cells
and vascular smooth muscle cells that can lead to ischemic heart disease; however, the …

Exosomal miR‐512‐3p derived from mesenchymal stem cells inhibits oxidized low‐density lipoprotein‐induced vascular endothelial cells dysfunction via regulating …

S Chen, H Zhou, B Zhang, Q Hu - Journal of biochemical and …, 2021 - Wiley Online Library
Atherosclerosis (AS) is a prevalent chronic inflammatory vascular disease. Upregulated
oxidized low‐density lipoprotein (ox‐LDL) in the serum has been found to induce …