Sixty‐six confirmed instances of clinically metachronous second breast cancers were
encountered over a 10‐year period in 1578 women with invasive breast cancer enrolled in …

The importance of the other breast when cancer is found in the first has been a subject of
controversy, especially as related to: the determination of whether a cancer in the other …

The presence of bilateral invasive breast cancer places the patient in a state of double
jeopardy. At Memorial Sloan‐Kettering Cancer Center, the overall 10‐year recurrence rate …

Microscopic foci of multicentric cancer were detected in 121 of 904 breasts surgically
removed for a clinically overt, invasive cancer. This incidence of 13.4% is regarded as a …

Bilateral breast cancer is discussed as to 1) the criteria for determining whether a cancer in
the other breast is primary or metastatic; 2) the incidence of simultaneous and subsequent …

ORTY-THREE YEARS AGO, IN 1921, THE! &YEAR survival rate for breast cancer patients
had reached 30%. In that year, K ilg~ re~~ wrote the first major paper concerned with the risk …

Although survival from primary breast cancer has improved with earlier diagnosis and
treatment, the management of the opposite breast is still in question. The risk factors for …

Seventy-eight confirmed cases of second primary breast cancer in the contralateral breast
were encountered over a 22-year period in 1332 women with invasive breast cancer treated …

One hundred ten local breast recurrences were observed in 1108 pathologically evaluable
patients enrolled in NSABP protocol 6 who were treated by lumpectomy and followed for 5 to …

1. When a woman has had a cancer of one breast, the risk of cancer in the opposite breast is
a significant one that cannot be ignored. 2.2. As evidence of this, the prophylactic removal of …