Observational studies of inhaled corticosteroid effectiveness in COPD: lessons learned

S Suissa, P Ernst - Chest, 2018 - Elsevier
Background Randomized controlled trials at times investigate findings suggested by
observational studies. For example, the Towards a Revolution in COPD Health (TORCH) …

Rational use of inhaled corticosteroids for the treatment of COPD: a plain language summary

A Ariel, PJ Barnes, T Maricoto… - Journal of …, 2023 - becarispublishing.com
What is this summary about? Inhaled corticosteroids (ICS) are a type of medication delivered
via an inhaler device that are commonly used in the treatment of asthma. ICS can also be …

Efficacy and safety of inhaled corticosteroids in patients with COPD: a systematic review and meta-analysis of health outcomes

G Gartlehner, RA Hansen, SS Carson… - The Annals of Family …, 2006 - Annals Family Med
PURPOSE We wanted to review systematically the efficacy, effectiveness, and safety of
inhaled corticosteroids with respect to health outcomes in patients with chronic obstructive …

Withdrawal of inhaled corticosteroids in individuals with COPD-a systematic review and comment on trial methodology

NJ Nadeem, SJC Taylor, SM Eldridge - Respiratory research, 2011 - Springer
Inhaled corticosteroids (ICS) reduce COPD exacerbation frequency and slow decline in
health related quality of life but have little effect on lung function, do not reduce mortality, and …

Treatment implications on morbidity and mortality in COPD

DW Mapel - Chest, 2004 - Elsevier
Inhaled corticosteroids (ICSs) remain controversial in COPD, although recent clinical trials
have consistently found that they reduce chronic respiratory symptoms and, in some …

The dose of inhaled corticosteroids in patients with COPD: when less is better

JL Izquierdo, BG Cosio - International Journal of Chronic …, 2018 - Taylor & Francis
Background The use of inhaled corticosteroids (ICS) in combination with bronchodilators in
patients with COPD has been shown to decrease the rate of disease exacerbations and to …

Association of inhaled corticosteroids with all-cause mortality risk in patients with COPD: a meta-analysis of 60 randomized controlled trials

H Chen, ZX Deng, J Sun, Q Huang, L Huang, YH He… - Chest, 2023 - Elsevier
Background Inhaled corticosteroids (ICSs) have been used widely in the maintenance
therapy of COPD. However, whether inhaled therapy containing ICSs can reduce the all …

Inhaled corticosteroids vs placebo for preventing COPD exacerbations: a systematic review and metaregression of randomized controlled trials

R Agarwal, AN Aggarwal, D Gupta, SK Jindal - Chest, 2010 - Elsevier
Background Inhaled corticosteroids (ICS) have been shown to decrease the occurrence of
COPD exacerbations. However, the relationship of baseline lung function and reduction of …

Managing the safety of inhaled corticosteroids in COPD and the risk of pneumonia

A Liapikou, M Toumbis, A Torres - Expert Opinion on Drug Safety, 2015 - Taylor & Francis
Introduction: Inhaled corticosteroids (ICS) are known to increase the risk of pneumonia in
patients with chronic obstructive pulmonary disease. To estimate the association between …

Another piece of the inhaled corticosteroids-in-COPD puzzle

J Vestbo - American Journal of Respiratory and Critical Care …, 2001 - atsjournals.org
In this issue of AJRCCM, Sin and Tu (pp. 580–584) publish their exciting
pharmacoepidemiologic study of inhaled corticosteroids (ICS) in the elderly (1). Using …