The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules
SJ Archibald, L Allott - EJNMMI radiopharmacy and chemistry, 2021 - Springer
Abstract The aluminium-[18F] fluoride ([18F] AlF) radiolabelling method combines the
favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal …
favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal …
A Comprehensive Review of Non-Covalent Radiofluorination Approaches Using Aluminum [18F]fluoride: Will [18F]AlF Replace 68Ga for Metal Chelate Labeling?
C Fersing, A Bouhlel, C Cantelli, P Garrigue… - Molecules, 2019 - mdpi.com
Due to its ideal physical properties, fluorine-18 turns out to be a key radionuclide for positron
emission tomography (PET) imaging, for both preclinical and clinical applications. However …
emission tomography (PET) imaging, for both preclinical and clinical applications. However …
A general [18 F] AlF radiochemistry procedure on two automated synthesis platforms
L Allott, C Da Pieve, DR Turton, G Smith - Reaction Chemistry & …, 2017 - pubs.rsc.org
The aluminium fluoride-18 ([18F] AlF) radiolabelling procedure has generated great interest
because it is a simple, one-pot method that can be used to directly radiolabel small …
because it is a simple, one-pot method that can be used to directly radiolabel small …
Radiochemistry with {Al18F} 2+: Current status and optimization perspectives for efficient radiofluorination by complexation
S Schmitt, E Moreau - Coordination Chemistry Reviews, 2023 - Elsevier
With the aim to efficiently develop and synthesize new radiotracers for PET imaging, and
their use for theranostic approaches, radiolabeling technics have not ceased to progress …
their use for theranostic approaches, radiolabeling technics have not ceased to progress …
Fluorine-18: A radionuclide with diverse range of radiochemistry and synthesis strategies for target based PET diagnosis
Fluorine-18 is one of the most widely used radionuclides for the production of
radiopharmaceuticals for positron emission tomography (PET). The radiolabeling methods …
radiopharmaceuticals for positron emission tomography (PET). The radiolabeling methods …
Fluorine-18 radiochemistry, labeling strategies and synthetic routes
O Jacobson, DO Kiesewetter, X Chen - Bioconjugate chemistry, 2015 - ACS Publications
Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET)
radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …
radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …
New Chelators for Low Temperature Al18F-Labeling of Biomolecules
F Cleeren, J Lecina, EMF Billaud… - Bioconjugate …, 2016 - ACS Publications
The Al18F labeling method is a relatively new approach that allows radiofluorination of
biomolecules such as peptides and proteins in a one-step procedure and in aqueous …
biomolecules such as peptides and proteins in a one-step procedure and in aqueous …
[18 F]-Group 13 fluoride derivatives as radiotracers for positron emission tomography
The field of 18F chemistry is rapidly expanding because of the use of this radionuclide in
radiotracers for positron emission tomography (PET). Until recently, most [18F]-radiotracers …
radiotracers for positron emission tomography (PET). Until recently, most [18F]-radiotracers …
New Strategies for Rapid 18F-Radiolabeling of Biomolecules for Radionuclide-Based In Vivo Imaging
JL Zeng, J Wang, JA Ma - Bioconjugate chemistry, 2015 - ACS Publications
The increasing availability of highly active no-carrier-added [18F]-fluoride makes its use in
radiolabeling biomolecules attractive. By incorporating “fluorophilic” elements (Si, B, and Al) …
radiolabeling biomolecules attractive. By incorporating “fluorophilic” elements (Si, B, and Al) …
Al18F labeling of peptides and proteins
P Laverman, WJ McBride, RM Sharkey… - Journal of Labelled …, 2014 - Wiley Online Library
Radiolabeled receptor‐binding peptides and proteins have emerged as an important class
of radiopharmaceuticals that have changed radionuclide imaging in clinical practice. Many …
of radiopharmaceuticals that have changed radionuclide imaging in clinical practice. Many …