Successful evolutionary enzyme engineering requires a high throughput screening or
selection method, which considerably increases the chance of obtaining desired properties …

Enzymes have been long used in man-made biochemical processes, from brewing and
fermentation to current industrial production of fine chemicals. The ever-growing demand for …

Enzymes are versatile catalysts and their synthetic potential has been recognized for a long
time. In order to exploit their full potential, enzymes often need to be re-engineered or …

Current challenges and promises of white biotechnology encourage protein engineers to
use a directed evolution approach to generate novel and useful biocatalysts for various sets …

Directed evolution has matured to a routinely applied algorithm to tailor enzyme properties
to meet the demands in various applications. In order to free directed enzyme evolution from …

Enzymes are increasingly being used as biocatalysts in the generation of products that have
until now been derived using traditional chemical processes. Such products range from …

Enzymes have the potential to catalyse a wide variety of chemical reactions. They are
increasingly being sought as environmentally friendly and cost‐effective alternatives to …

As an important sector of the chemical industry, biocatalysis requires the continuous
development of enzymes with tailor-made activity, selectivity, stability, or tolerance to …

With increasing concerns in sustainable development, biocatalysis has been recognized as
a competitive alternative to traditional chemical routes in the past decades. As nature's …

In the past decade methods of directed molecular evolution have proven revolutionary in
protein engineering. An increasing number of powerful new combinatorial techniques have …