A high level of homocysteine (Hcy) is associated with oxidative/ER stress, apoptosis, and
impairment of angiogenesis, whereas hydrogen sulfide (H2S) has been found to reverse this …

Significance: Cancer is a complex and heterotypic structure with a spatial organization that
contributes to challenges in therapeutics. Enzymes associated with producing the …

Significance: Cancer represents a major socioeconomic problem; there is a significant need
for novel therapeutic approaches targeting tumor-specific pathways. Recent Advances: In …

Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

Cysteine (Cys) is a semi-essential nutrient amino acid that plays an important role in cells
through endogenous production and various transport systems. Intracellular Cys can be …

Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …

Hydrogen sulfide (H2S) is an endogenously produced signaling molecule. The enzymes 3-
mercaptopyruvate sulfurtransferase (MST), partly localized in mitochondria, and the inner …

Hydrogen sulphide (H2S) is a gaseous neurotransmitter that can be self‐synthesized by
living organisms. With the deepening of research, the pathophysiological mechanisms of …

Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid derived in
methionine metabolism. The increased level of Hcy in plasma, hyperhomocysteinemia, is …

Abstract Hydrogen sulfide (H 2 S), while historically perceived merely as a toxicant, has
progressively emerged as a key regulator of numerous processes in mammalian physiology …