Adenosine: physiology, pharmacology, and clinical applications
Adenosine is a ubiquitous extracellular signaling molecule with essential functions in human
physiology. Due to the widespread expression of adenosine receptors, it has far-reaching …
physiology. Due to the widespread expression of adenosine receptors, it has far-reaching …
Adenosine and adenosine receptor-mediated action in coronary microcirculation
Y Zhang, B Wernly, X Cao, SJ Mustafa, Y Tang… - Basic Research in …, 2021 - Springer
Adenosine is an ubiquitous extracellular signaling molecule and plays a fundamental role in
the regulation of coronary microcirculation through activation of adenosine receptors (ARs) …
the regulation of coronary microcirculation through activation of adenosine receptors (ARs) …
Adenosine and the cardiovascular system: the good and the bad
R Guieu, JC Deharo, B Maille, L Crotti… - Journal of clinical …, 2020 - mdpi.com
Adenosine is a nucleoside that impacts the cardiovascular system via the activation of its
membrane receptors, named A1R, A2AR, A2BR and A3R. Adenosine is released during …
membrane receptors, named A1R, A2AR, A2BR and A3R. Adenosine is released during …
Harnessing an endogenous cardioprotective mechanism: cellular sources and sites of action of adenosine
K Mullane, D Bullough - Journal of molecular and cellular cardiology, 1995 - Elsevier
Endogenous adenosine is produced by the heart during ischemia-reperfusion as a natural
cardioprotectant. The benefits of this local protective mechanism can be harnessed by …
cardioprotectant. The benefits of this local protective mechanism can be harnessed by …
Adenosine, the heart, and coronary circulation.
M Hori, M Kitakaze - Hypertension, 1991 - Am Heart Assoc
Adenosine is known to regulate myocardial and coronary circulatory functions. Adenosine
not only dilates coronary vessels, but attenuates beta-adrenergic receptor-mediated …
not only dilates coronary vessels, but attenuates beta-adrenergic receptor-mediated …
[HTML][HTML] Adenosine and its receptors in the heart: regulation, retaliation and adaptation
The purine nucleoside adenosine is an important regulator within the cardiovascular system,
and throughout the body. Released in response to perturbations in energy state, among …
and throughout the body. Released in response to perturbations in energy state, among …
Adenosine and the cardiovascular system
AB Reiss, D Grossfeld, LJ Kasselman… - American Journal of …, 2019 - Springer
Adenosine is an endogenous nucleoside with a short half-life that regulates many
physiological functions involving the heart and cardiovascular system. Among the …
physiological functions involving the heart and cardiovascular system. Among the …
Intracoronary adenosine: dose–response relationship with hyperemia
J Adjedj, GG Toth, NP Johnson, M Pellicano… - Cardiovascular …, 2015 - jacc.org
Objectives The present study sought to establish the dosage of intracoronary (IC) adenosine
associated with minimal side effects and above which no further increase in flow can be …
associated with minimal side effects and above which no further increase in flow can be …
Cardiovascular adenosine receptors: expression, actions and interactions
JP Headrick, KJ Ashton, RB Rose'Meyer… - Pharmacology & …, 2013 - Elsevier
Intra-and extracellular adenosine levels rise in response to physiological stimuli and with
metabolic/energetic perturbations, inflammatory challenge and tissue injury. Extracellular …
metabolic/energetic perturbations, inflammatory challenge and tissue injury. Extracellular …
[图书][B] Adenosine receptors and the heart: role in regulation of coronary blood flow and cardiac electrophysiology
SJ Mustafa, RR Morrison, B Teng, A Pelleg - 2009 - Springer
Adenosine is an autacoid that plays a critical role in regulating cardiac function, including
heart rate, contractility, and coronary flow. In this chapter, current knowledge of the functions …
heart rate, contractility, and coronary flow. In this chapter, current knowledge of the functions …