Swab-in-Capillary Electrospray Ionization and a Miniature Mass Spectrometer for In Situ Drug Analysis

S Liu, W Xu, Y Zhai - Analytical Chemistry, 2023 - ACS Publications
In situ analysis of drugs has been in increasing demand in many fields. As an updated
version of capillary-in-capillary electrospray ionization (CC-ESI) developed previously, a …

Capillary-in-Capillary electrospray ionization (CC-ESI) source enabling convenient sampling and quantitative analysis for point-of-care testing

Q Liang, S Liu, W Xu, Y Zhai - Analytical Chemistry, 2023 - ACS Publications
With outstanding analytical performances, mass spectrometry (MS) has shown great
potential for clinical applications. To facilitate the sampling process and quantitative …

Remote sampling mass spectrometry for dry samples: Sheath‐flow probe electrospray ionization (PESI) using a gel‐loading tip inserted with an acupuncture needle

DT Usmanov, KB Ashurov, S Ninomiya… - Rapid …, 2018 - Wiley Online Library
Rationale Probe electrospray ionization (PESI) is only applicable to liquid or wet samples. In
this study, a sheath‐flow PESI method for remote sampling mass spectrometry that can be …

Direct electrospray ionization mass spectrometric profiling of real-world samples via a solid sampling probe

Z Yu, LC Chen, MK Mandal, K Yoshimura… - Journal of The …, 2013 - ACS Publications
This study presents a novel direct analysis strategy for rapid mass spectrometric profiling of
biochemicals in real-world samples via a direct sampling probe (DSP) without sample …

Pharmaceutical cleaning validation using non‐proximate large‐area desorption electrospray ionization mass spectrometry

S Soparawalla, GA Salazar, RH Perry… - … Journal Devoted to …, 2009 - Wiley Online Library
Desorption electrospray ionization (DESI) is a droplet‐based ionization method that is
applied to samples in the ambient environment with little or no sample preparation. Its utility …

Analysis of biological fluids by direct combination of solid phase extraction and desorption electrospray ionization mass spectrometry

J Denes, M Katona, A Hosszu, N Czuczy… - Analytical …, 2009 - ACS Publications
A novel, solid phase extraction (SPE)-based sample preparation method was developed for
desorption electrospray ionization (DESI) mass spectrometry. Conventional SPE sample …

Chip-based solid-phase extraction pretreatment for direct electrospray mass spectrometry analysis using an array of monolithic columns in a polymeric substrate

A Tan, S Benetton, JD Henion - Analytical chemistry, 2003 - ACS Publications
An array of eight porous monolithic columns, prepared in a Zeonor polymeric chip by UV-
initiated polymerization of butyl methacrylate and ethylene dimethacrylate, was tested for …

Direct detection of trace level illicit drugs in human body fluids by probe electrospray ionization mass spectrometry (PESI-MS)

S Saha, MK Mandal, K Hiraoka - Analytical Methods, 2013 - pubs.rsc.org
Detection of illicit drugs by ambient mass spectrometry has been gaining attention due to the
unique advantage of detecting trace levels of chemicals from complex matrices without or …

High-throughput quantitative analysis by desorption electrospray ionization mass spectrometry

NE Manicke, T Kistler, DR Ifa, RG Cooks… - Journal of the …, 2011 - ACS Publications
A newly developed high-throughput desorption electrospray ionization (DESI) source was
characterized in terms of its performance in quantitative analysis. A 96-sample array …

Solid-phase microextraction-probe electrospray ionization devices for screening and quantitating drugs of abuse in small amounts of biofluids

M Thirukumaran, V Singh, Y Arao, Y Fujito… - Talanta, 2021 - Elsevier
Probe electrospray ionization (PESI) is an ambient ionization mass spectrometry technique
(AIMS) that is primarily used in qualitative studies, though researchers have recently …