[HTML][HTML] Galangin loaded galactosylated pluronic F68 polymeric micelles for liver targeting

S Patil, V Ujalambkar, A Rathore, S Rojatkar… - Biomedicine & …, 2019 - Elsevier
Galangin possess wide range of pharmacological activities including antiarthritic,
hepatoprotective, anti-inflammatory, antibacterial, and anticancer especially in …

Harmine-loaded galactosylated pluronic F68-gelucire 44/14 mixed micelles for liver targeting

J Prasad Kushwaha, D Baidya… - Drug Development and …, 2019 - Taylor & Francis
Harmine (HM), a phytoconstituent has wide range of pharmacological activities including
antimicrobial, antifungal, antioxidative, and anticancer. HM has shown promising anticancer …

Formulation, characterization, and evaluation of the anti-tumor activity of nanosized galangin loaded niosomes on chemically induced hepatocellular carcinoma in rats

S Sabry, T Okda, A Hasan - Journal of Drug Delivery Science and …, 2021 - Elsevier
Galangin (GAL) is a flavonoid with anti-tumor activity. However, its poor solubility results in
low bioavailability thus hindering its clinical application. To overcome this challenge, we …

Galangin-loaded, liver targeting liposomes: Optimization and hepatoprotective efficacy

J Zhu, Q Wang, H Li, H Zhang, Y Zhu… - Journal of Drug Delivery …, 2018 - Elsevier
The aim of this study was to develop liver targeting galangin-loaded liposomes (Galangin-
Liposomes) and evaluate their oral bioavailability. Box Behnken design was applied to …

Gambogic acid grafted low molecular weight heparin micelles for targeted treatment in a hepatocellular carcinoma model with an enhanced anti-angiogenesis effect

X Yan, Y Yang, L He, D Peng, D Yin - International Journal of …, 2017 - Elsevier
Gambogic acid (GA) is a potential anti-cancer agent with poor water-solubility, whereas
heparin has anti-angiogenesis effects with good hydrophilicity. In this study, GA grafted low …

Polymeric nano-micelles as novel cargo-carriers for LY2157299 liver cancer cells delivery

NAN Hanafy, A Quarta, MM Ferraro, L Dini… - International journal of …, 2018 - mdpi.com
LY2157299 (LY), which is very small molecule bringing high cancer diffusion, is a pathway
antagonist against TGFβ. LY dosage can be diluted by blood plasma, can be captured by …

Preparation and characterization of galactosylated glycol chitosan micelles and its potential use for hepatoma-targeting delivery of doxorubicin

JM Yu, WD Li, L Lu, XY Zhou, DY Wang, HM Li… - Journal of Materials …, 2014 - Springer
This study aimed to develop novel galactosylated cholesterol modified-glycol chitosan (Gal-
CHGC) micelles for targeting delivery of doxorubicin (DOX) in live cancer cells. Three kinds …

Glycyrrhetinic acid‐poly (ethylene glycol)‐glycyrrhetinic acid tri‐block conjugates based self‐assembled micelles for hepatic targeted delivery of poorly water soluble …

F Wu, T Xu, C Liu, C Chen, X Song… - The Scientific World …, 2013 - Wiley Online Library
The triblock 18β‐glycyrrhetinic acid‐poly (ethylene glycol)‐18β‐glycyrrhetinic acid
conjugates (GA‐PEG‐GA) based self‐assembled micelles were synthesized and …

TPGS-g-PLGA/Pluronic F68 mixed micelles for tanshinone IIA delivery in cancer therapy

J Zhang, Y Li, X Fang, D Zhou, Y Wang… - International journal of …, 2014 - Elsevier
Tanshinone IIA (TAN) has few clinical applications for anti-cancer therapy mainly due to its
high lipophicity, low cellular uptake, and poor bioavailability. To improve the anti-cancer …

Apocynin-loaded PLGA nanomedicine tailored with galactosylated chitosan intrigue asialoglycoprotein receptor in hepatic carcinoma: prospective targeted therapy

HM Anter, RM Aman, DIA Othman, KM Elamin… - International Journal of …, 2023 - Elsevier
Nature serves as a priceless source for phytomedicines to treat different types of cancer,
including hepatocellular carcinoma (HCC). Apocynin (APO), an anti-cancer phytomedicine …