[HTML][HTML] Galangin loaded galactosylated pluronic F68 polymeric micelles for liver targeting
Galangin possess wide range of pharmacological activities including antiarthritic,
hepatoprotective, anti-inflammatory, antibacterial, and anticancer especially in …
hepatoprotective, anti-inflammatory, antibacterial, and anticancer especially in …
Harmine-loaded galactosylated pluronic F68-gelucire 44/14 mixed micelles for liver targeting
J Prasad Kushwaha, D Baidya… - Drug Development and …, 2019 - Taylor & Francis
Harmine (HM), a phytoconstituent has wide range of pharmacological activities including
antimicrobial, antifungal, antioxidative, and anticancer. HM has shown promising anticancer …
antimicrobial, antifungal, antioxidative, and anticancer. HM has shown promising anticancer …
Formulation, characterization, and evaluation of the anti-tumor activity of nanosized galangin loaded niosomes on chemically induced hepatocellular carcinoma in rats
Galangin (GAL) is a flavonoid with anti-tumor activity. However, its poor solubility results in
low bioavailability thus hindering its clinical application. To overcome this challenge, we …
low bioavailability thus hindering its clinical application. To overcome this challenge, we …
Galangin-loaded, liver targeting liposomes: Optimization and hepatoprotective efficacy
J Zhu, Q Wang, H Li, H Zhang, Y Zhu… - Journal of Drug Delivery …, 2018 - Elsevier
The aim of this study was to develop liver targeting galangin-loaded liposomes (Galangin-
Liposomes) and evaluate their oral bioavailability. Box Behnken design was applied to …
Liposomes) and evaluate their oral bioavailability. Box Behnken design was applied to …
Gambogic acid grafted low molecular weight heparin micelles for targeted treatment in a hepatocellular carcinoma model with an enhanced anti-angiogenesis effect
X Yan, Y Yang, L He, D Peng, D Yin - International Journal of …, 2017 - Elsevier
Gambogic acid (GA) is a potential anti-cancer agent with poor water-solubility, whereas
heparin has anti-angiogenesis effects with good hydrophilicity. In this study, GA grafted low …
heparin has anti-angiogenesis effects with good hydrophilicity. In this study, GA grafted low …
Polymeric nano-micelles as novel cargo-carriers for LY2157299 liver cancer cells delivery
NAN Hanafy, A Quarta, MM Ferraro, L Dini… - International journal of …, 2018 - mdpi.com
LY2157299 (LY), which is very small molecule bringing high cancer diffusion, is a pathway
antagonist against TGFβ. LY dosage can be diluted by blood plasma, can be captured by …
antagonist against TGFβ. LY dosage can be diluted by blood plasma, can be captured by …
Preparation and characterization of galactosylated glycol chitosan micelles and its potential use for hepatoma-targeting delivery of doxorubicin
This study aimed to develop novel galactosylated cholesterol modified-glycol chitosan (Gal-
CHGC) micelles for targeting delivery of doxorubicin (DOX) in live cancer cells. Three kinds …
CHGC) micelles for targeting delivery of doxorubicin (DOX) in live cancer cells. Three kinds …
Glycyrrhetinic acid‐poly (ethylene glycol)‐glycyrrhetinic acid tri‐block conjugates based self‐assembled micelles for hepatic targeted delivery of poorly water soluble …
F Wu, T Xu, C Liu, C Chen, X Song… - The Scientific World …, 2013 - Wiley Online Library
The triblock 18β‐glycyrrhetinic acid‐poly (ethylene glycol)‐18β‐glycyrrhetinic acid
conjugates (GA‐PEG‐GA) based self‐assembled micelles were synthesized and …
conjugates (GA‐PEG‐GA) based self‐assembled micelles were synthesized and …
TPGS-g-PLGA/Pluronic F68 mixed micelles for tanshinone IIA delivery in cancer therapy
Tanshinone IIA (TAN) has few clinical applications for anti-cancer therapy mainly due to its
high lipophicity, low cellular uptake, and poor bioavailability. To improve the anti-cancer …
high lipophicity, low cellular uptake, and poor bioavailability. To improve the anti-cancer …
Apocynin-loaded PLGA nanomedicine tailored with galactosylated chitosan intrigue asialoglycoprotein receptor in hepatic carcinoma: prospective targeted therapy
Nature serves as a priceless source for phytomedicines to treat different types of cancer,
including hepatocellular carcinoma (HCC). Apocynin (APO), an anti-cancer phytomedicine …
including hepatocellular carcinoma (HCC). Apocynin (APO), an anti-cancer phytomedicine …