Repeated cycles of binge alcohol drinking and abstinence are key components in the
development of dependence. However, the precise behavioral mechanisms underlying …

Interactions between ethanol and synaptic transmission mediated by γ-amino-N-butyric acid
(GABA) have been suggested to contribute to alcohol intoxication. Ethanol effects on …

For almost three decades now, the GABAergic synapse has been the focus of intense study
for its putative role in mediating many of the behavioral consequences associated with acute …

The mesolimbic dopaminergic system, originating from the ventral tegmental area (VTA) is
implicated in the rewarding properties of ethanol. VTA dopaminergic neurons are under the …

Binge alcohol (ethanol) drinking is a destructive pattern of ethanol consumption that may
precipitate ethanol dependence—a chronic, debilitating, and prevalent health problem …

The nucleus accumbens (NAcc) may be a key area in the rewarding effects of abused drugs.
We previously showed that low ethanol concentrations decreased both N-methyl-d …

The present study used conventional and quantitative microdialysis to assess glutamatergic
and GABAergic neurotransmission in the hippocampal CA3 area of the rat following a …

The central nucleus of amygdala (CeA) is important in regulating alcohol consumption and
plays a major role in the anxiogenic response to ethanol withdrawal. We showed previously …

Drinking to intoxication or binge drinking is a hallmark characteristic of alcohol abuse.
Although hard to model in rodents, the scheduled high alcohol consumption (SHAC) …

Background: Activation of the dopaminergic (DA) neurons of the ventral tegmental area
(VTA) by ethanol has been implicated in its rewarding and reinforcing effects. At most central …