[HTML][HTML] Home exercise, branched-chain amino acids, and probiotics improve frailty in cirrhosis: A randomized clinical trial

E Román, N Kaür, E Sánchez, M Poca… - Hepatology …, 2024 - journals.lww.com
Background: Frailty is a predictive factor of hospitalization, falls, and mortality in patients with
cirrhosis, regardless of the degree of liver failure. The aim was to analyze whether a …

[HTML][HTML] Branched-chain amino acids supplementation improves liver frailty index in frail compensated cirrhotic patients: a randomized controlled trial

S Siramolpiwat, N Limthanetkul, B Pornthisarn… - BMC …, 2023 - Springer
Background Physical frailty is related with morbidity and mortality in patients with cirrhosis.
Currently, there is no approved treatment of frailty in these patients. Here, we evaluated the …

Accumulating awareness on the clinical significance and relevance of frailty in cirrhosis: Time to dig deeper into mechanistic basis!

Y Deng, Y Hui, B Cui, W Xie, C Sun - Liver International, 2023 - Wiley Online Library
Frailty corresponds to an emerging construct in the hepatology which is originally introduced
as a validated geriatric syndrome regarding increased vulnerability to pathophysiological …

Tale of the Frail: Understanding Frailty in Cirrhosis.

F Pradhan, N Narang, M Fallon - Southern Medical Journal, 2021 - europepmc.org
Frailty is a dynamic condition that results in increased vulnerability to health stressors. Often
associated with older adults, frailty is not limited to the geriatric population, although aging …

Exercise only works if you do it! The holy grail of adherence

B Kok, M McNeely, M Watt… - Official journal of the …, 2021 - journals.lww.com
Exercise interventions in patients with cirrhosis have been shown to improve muscle mass
and strength, aerobic capacity, fatigue, and quality of life. There are gaps, however …

Frailty is associated with increased risk of cirrhosis disease progression and death

S Wang, R Whitlock, C Xu, S Taneja, S Singh… - …, 2022 - Wiley Online Library
Abstract Background and Aims The Liver Frailty Index (LFI) is a well‐studied tool that
evaluates frailty in patients with cirrhosis. Consisting of grip strength, chair stands, and …

[PDF][PDF] Standard assessments of frailty are validated predictors of mortality in hospitalized patients with cirrhosis

EB Tapper, D Finkelstein, MA Mittleman… - …, 2015 - Wiley Online Library
The risk of morbidity and mortality for hospitalized patients with cirrhosis is high and
incompletely captured by conventional indices. We sought to evaluate the predictive role of …

Frailty in outpatients with cirrhosis: a prospective observational study

E Román, M Parramón, M Flavià, C Gely… - Liver …, 2021 - Wiley Online Library
Abstract Background and Aim Frailty is increasingly recognized as a major prognostic factor
in cirrhosis in addition to conventional liver insufficiency scores. The aim was to compare the …

[PDF][PDF] Effect of a multistrain probiotic on cognitive function and risk of falls in patients with cirrhosis: a randomized trial

E Román, JC Nieto, C Gely, S Vidal… - Hepatology …, 2019 - Wiley Online Library
Probiotics can modulate gut microbiota, intestinal permeability, and immune response and
could therefore improve cognitive dysfunction and help avoid potential consequences, such …

Home‐based intensive nutrition therapy improves frailty and sarcopenia in patients with decompensated cirrhosis: A randomized clinical trial

BL Meena, S Taneja, P Tandon, N Sahni… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Aim The majority of patients with decompensated cirrhosis suffer
from malnutrition, a potentially modifiable contributor to frailty and sarcopenia. The present …