Thyroid hormones in male reproductive development: evidence for direct crosstalk between the androgen and thyroid hormone axes

DEK Flood, JI Fernandino, VS Langlois - General and comparative …, 2013 - Elsevier
Thyroid hormones (THs) exert a broad range of effects on development in vertebrate
species, demonstrating connections in nearly every biological endocrine system. In …

Mechanisms of crosstalk between endocrine systems: regulation of sex steroid hormone synthesis and action by thyroid hormones

P Duarte-Guterman, L Navarro-Martín… - General and comparative …, 2014 - Elsevier
Thyroid hormones (THs) are well-known regulators of development and metabolism in
vertebrates. There is increasing evidence that THs are also involved in gonadal …

[HTML][HTML] Crossover of the hypothalamic pituitary–adrenal/interrenal,–thyroid, and–gonadal axes in testicular development

DC Castañeda Cortés, VS Langlois… - Frontiers in …, 2014 - frontiersin.org
Besides the well-known function of thyroid hormones (THs) for regulating metabolism, it has
recently been discovered that THs are also involved in testicular development in mammalian …

Effects of thyroid endocrine manipulation on sex-related gene expression and population sex ratios in Zebrafish

P Sharma, S Tang, GD Mayer, R Patiño - General and Comparative …, 2016 - Elsevier
Thyroid hormone reportedly induces masculinization of genetic females and goitrogen
treatment delays testicular differentiation (ovary-to-testis transformation) in genetic males of …

Thyroid Hormone Stimulates the Proliferation of Sertoli Cells and Single Type A Spermatogonia in Adult Zebrafish (Danio rerio) Testis

R Morais, RH Nóbrega, NE Gómez-González… - …, 2013 - academic.oup.com
Thyroid hormones participate in regulating growth and homeostatic processes in
vertebrates, including development and adult functioning of the reproductive system. Here …

Thyroid hormone receptors and ligands, tissue distribution and sexual behavior

E Carosa, A Lenzi, EA Jannini - Molecular and cellular endocrinology, 2018 - Elsevier
The thyroid hormones (THs) triiodothyronine (T 3) and tetraiodothyronine, or thyroxine (T 4),
not only dramatically impact on development and differentiation, but also on the sexual and …

Thyroid hormone action in the developing testis: intergenerational epigenetics

A Hernandez, ME Martinez - Journal of Endocrinology, 2020 - joe.bioscientifica.com
Male fertility involves the successful transmission of the genetic code to the next generation.
It requires appropriately timed cellular processes during testis development, adequate …

Evolution of thyroid hormone signaling in animals: Non-genomic and genomic modes of action

E Taylor, A Heyland - Molecular and cellular endocrinology, 2017 - Elsevier
Much research has focused on vertebrate thyroid hormone (TH) synthesis and their function
in development and metabolism. While important differences in TH synthesis and signaling …

Expression profiles of reproduction-and thyroid hormone-related transcripts in the brains of chemically-induced intersex frogs

VS Langlois, P Duarte-Guterman, VL Trudeau - Sexual Development, 2011 - karger.com
Endocrine disrupting chemicals can induce intersex animals in amphibians and fish. Our
previous study in frogs demonstrated that chemically-induced intersex animals can display …

The hypothalamic–pituitary–thyroid axis and biological rhythms: the discovery of TSH's unexpected role using animal models

K Ikegami, T Yoshimura - Best Practice & Research Clinical Endocrinology …, 2017 - Elsevier
Thyroid hormones (TH) are important for development, growth, and metabolism. It is also
clear that the synthesis and secretion of TH are regulated by the hypothalamic–pituitary …