[HTML][HTML] In vivo biocompatibility, clearance, and biodistribution of albumin vehicles for pulmonary drug delivery

A Woods, A Patel, D Spina, Y Riffo-Vasquez… - Journal of Controlled …, 2015 - Elsevier
The development of clinically acceptable albumin-based nanoparticle formulations for use in
pulmonary drug delivery has been hindered by concerns about the toxicity of nanomaterials …

Albumin nanocarriers for pulmonary drug delivery: An attractive approach

M Joshi, M Nagarsenkar, B Prabhakar - Journal of Drug Delivery Science …, 2020 - Elsevier
Biodegradable polymers are drawing a great deal of attention in the field of nanotechnology.
Albumin, abundantly present in human body, is a biocompatible and biodegradable polymer …

Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery …

JP Ibrahim, NJ Butcher, A Kothapalli… - Expert Opinion on …, 2023 - Taylor & Francis
Objectives Drug delivery systems typically show limited access to the lung interstitium and
absorption after pulmonary delivery. The aim of this work was to undertake a proof-of …

Recent advancement on albumin nanoparticles in treating lung carcinoma

Sristi, M Fatima, A Sheikh, WH Almalki… - Journal of Drug …, 2023 - Taylor & Francis
With the advancement of nanotechnology, many different forms of nanoparticles (NPs) are
created, which specifically enhance anticancer drug delivery to tumour cells. Albumin bio …

Nanoparticles for drug delivery to the lungs

JC Sung, BL Pulliam, DA Edwards - Trends in biotechnology, 2007 - cell.com
The lungs are an attractive route for non-invasive drug delivery with advantages for both
systemic and local applications. Incorporating therapeutics with polymeric nanoparticles …

Navigating albumin-based nanoparticles through various drug delivery routes

YL Tan, HK Ho - Drug discovery today, 2018 - Elsevier
Highlights•Albumin-based nanoparticles have excellent safety profile and targeting
properties which facilitates effective drug delivery.•The versatility of albumin-based …

[HTML][HTML] Albumin and functionalized albumin nanoparticles: Production strategies, characterization, and target indications

A Srivastava, A Prajapati - Asian Biomedicine, 2020 - sciendo.com
The inherent properties of albumin facilitate its effective use as a raw material to prepare a
nanosized drug delivery vehicles. Because of the enhanced surface area, biocompatibility …

Intestinal uptake and transport of albumin nanoparticles: Potential for oral delivery

L Hashem, M Swedrowska, D Vllasaliu - Nanomedicine, 2018 - Taylor & Francis
Aim: To explore the potential of albumin nanoparticles for oral drug delivery. Methods: Sub-
150 nm human serum albumin nanoparticles were fabricated via a desolvation technique …

Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model

M Beck-Broichsitter, J Gauss, CB Packhaeuser… - International journal of …, 2009 - Elsevier
The use of colloidal carrier systems for pulmonary drug delivery is an emerging field of
interest in nanomedicine. The objective of this study was to compare the pulmonary …

Nanoparticle formulations in pulmonary drug delivery

MM Bailey, CJ Berkland - Medicinal research reviews, 2009 - Wiley Online Library
The advent of nanotechnology has reignited interest in the lungs as a major route of drug
delivery for both systemic and local treatments. The large surface area of the lungs and the …