Circulating stem cells and cardiovascular outcomes: from basic science to the clinic

GP Fadini, A Mehta, DS Dhindsa… - European heart …, 2020 - academic.oup.com
The cardiovascular and haematopoietic systems have fundamental inter-relationships
during development, as well as in health and disease of the adult organism. Although …

Role of progenitor endothelial cells in cardiovascular disease and upcoming therapies

A Kawamoto, T Asahara - Catheterization and Cardiovascular …, 2007 - Wiley Online Library
The field of cell‐based transplantation has expanded considerably and is poised to become
an established cardiovascular therapy in the near future. In this review, we will focus on …

Endothelial progenitor cells: functional characterization

C Urbich, S Dimmeler - Trends in cardiovascular medicine, 2004 - Elsevier
Increasing evidence suggests that circulating progenitor cells contribute to postnatal
neovascularization. These cells home to sites of ischemia, adopt an endothelial phenotype …

Endothelial progenitor cells: new perspectives and applications in cardiovascular therapies

G Marsboom, S Janssens - Expert review of cardiovascular therapy, 2008 - Taylor & Francis
For over 10 years, bone marrow-derived endothelial progenitor cells (EPCs) have been
studied as a novel biomarker to assess the severity of cardiovascular diseases, and as a …

Circulating endothelial (progenitor) cells reflect the state of the endothelium: vascular injury, repair and neovascularization

CB Hunting, WA Noort, JJ Zwaginga - Vox sanguinis, 2005 - Wiley Online Library
An increase in the number of circulating endothelial cells (CEC) and of bone marrow‐
derived endothelial progenitor cells (EPC) in the peripheral blood is associated with …

Bone marrow and circulating stem/progenitor cells for regenerative cardiovascular therapy

MA Alaiti, M Ishikawa, MA Costa - Translational Research, 2010 - Elsevier
Cardiovascular disease is the leading cause of death and disability in the Western world. In
addition to the advancement of current therapeutic approaches to reduce the associated …

Working hypothesis to redefine endothelial progenitor cells

DN Prater, J Case, DA Ingram, MC Yoder - Leukemia, 2007 - nature.com
Since 1997, postnatal vasculogenesis has been purported to be an important mechanism for
neoangiogenesis via bone marrow (BM)-derived circulating endothelial progenitor cells …

Are endothelial progenitor cells the real solution for cardiovascular diseases? Focus on controversies and perspectives

CR Balistreri, S Buffa, C Pisano, D Lio… - BioMed research …, 2015 - Wiley Online Library
Advanced knowledge in the field of stem cell biology and their ability to provide a cue for
counteracting several diseases are leading numerous researchers to focus their attention on …

Endothelial progenitor cells and cardiovascular disease

TFJ King, JH McDermott - Journal of Stem Cells, 2014 - search.proquest.com
Abstract Endothelial Progenitor Cells (EPC) are bone-marrow derived stem cells that are
postulated to contribute to postnatal vasculogenesis and to repair of damaged endothelium …

Endothelial progenitor cells as therapeutic vectors in cardiovascular disorders: from experimental models to human trials

J Ben-Shoshan, J George - Pharmacology & therapeutics, 2007 - Elsevier
Cell-based therapy approaches for the restoration of blood flow in ischemic organs has
recently received growing interest. A considerable number of reports have documented the …