Thiazolidine-2, 4-diones: Progress towards multifarious applications
VS Jain, DK Vora, CS Ramaa - Bioorganic & medicinal chemistry, 2013 - Elsevier
The promising activity shown by compounds containing thiazolidine-2, 4-dione nucleus in
numerous categories such as anti-hyperglycaemics, aldose reductase inhibitors, anti …
numerous categories such as anti-hyperglycaemics, aldose reductase inhibitors, anti …
Therapeutic journey of 2, 4-thiazolidinediones as a versatile scaffold: An insight into structure activity relationship
Thiazolidinedione is an important heterocyclic ring system, a pharmacophore and a
privileged scaffold in medicinal chemistry; is a derivative of thiazolidine ring which came into …
privileged scaffold in medicinal chemistry; is a derivative of thiazolidine ring which came into …
[HTML][HTML] The bioactivity of thiazolidin-4-ones: A short review of the most recent studies
D Mech, A Kurowska, N Trotsko - International Journal of Molecular …, 2021 - mdpi.com
Thiazolidin-4-ones is an important heterocyclic ring system of a pharmacophore and a
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …
[HTML][HTML] Biological potential of thiazolidinedione derivatives of synthetic origin
Sucheta, S Tahlan, PK Verma - Chemistry Central Journal, 2017 - Springer
Thiazolidinediones are sulfur containing pentacyclic compounds that are widely found
throughout nature in various forms. Thiazolidinedione nucleus is present in numerous …
throughout nature in various forms. Thiazolidinedione nucleus is present in numerous …
Synthetic and medicinal perspective of thiazolidinones: A review
In the modern scenario, thiazolidinone scaffold has emerged as a very potent scaffold as per
its clinical significance concerned. It has attracted the keen interest of the researchers due to …
its clinical significance concerned. It has attracted the keen interest of the researchers due to …
Thiazolidine-2, 4-diones as multi-targeted scaffold in medicinal chemistry: Potential anticancer agents
A variety of substituents on the thiazolidine-2, 4-dione (TZD) nucleus have provided a wide
spectrum of biological activities by the using of different mechanism on various target sites …
spectrum of biological activities by the using of different mechanism on various target sites …
Thiazolidine-2, 4-dione derivatives: programmed chemical weapons for key protein targets of various pathological conditions
Abstract Thiazolidine-2, 4-dione is an extensively explored heterocyclic nucleus for
designing of novel agents implicated for a wide variety of pathophysiological conditions, that …
designing of novel agents implicated for a wide variety of pathophysiological conditions, that …
Recent developments and biological activities of thiazolidinone derivatives: A review
Thiazolidinone is considered as a biologically important active scaffold that possesses
almost all types of biological activities. Successful introduction of ralitoline as a potent anti …
almost all types of biological activities. Successful introduction of ralitoline as a potent anti …
[HTML][HTML] Saturated five-membered thiazolidines and their derivatives: from synthesis to biological applications
In past decades, interdisciplinary research has been of great interest for scholars.
Thiazolidine motifs behave as a bridge between organic synthesis and medicinal chemistry …
Thiazolidine motifs behave as a bridge between organic synthesis and medicinal chemistry …
[HTML][HTML] An overview on medicinal perspective of thiazolidine-2, 4-dione: A remarkable scaffold in the treatment of type 2 diabetes
G Bansal, PV Thanikachalam, RK Maurya… - Journal of advanced …, 2020 - Elsevier
Diabetes or diabetes mellitus is a complex or polygenic disorder, which is characterized by
increased levels of glucose (hyperglycemia) and deficiency in insulin secretion or resistance …
increased levels of glucose (hyperglycemia) and deficiency in insulin secretion or resistance …