Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration
VW Skrivankova, RC Richmond, BAR Woolf… - bmj, 2021 - bmj.com
Mendelian randomisation (MR) studies allow a better understanding of the causal effects of
modifiable exposures on health outcomes, but the published evidence is often hampered by …
modifiable exposures on health outcomes, but the published evidence is often hampered by …
Strengthening the reporting of observational studies in epidemiology using Mendelian randomization: the STROBE-MR statement
VW Skrivankova, RC Richmond, BAR Woolf… - Jama, 2021 - jamanetwork.com
Importance Mendelian randomization (MR) studies use genetic variation associated with
modifiable exposures to assess their possible causal relationship with outcomes and aim to …
modifiable exposures to assess their possible causal relationship with outcomes and aim to …
Investigating the transparency of reporting in two-sample summary data Mendelian randomization studies using the MR-Base platform
Abstract Background Two-sample Mendelian randomization (2SMR) is an increasingly
popular epidemiological method that uses genetic variants as instruments for making causal …
popular epidemiological method that uses genetic variants as instruments for making causal …
Tools for assessing quality and risk of bias in Mendelian randomization studies: a systematic review
Abstract Background The use of Mendelian randomization (MR) in epidemiology has
increased considerably in recent years, with a subsequent increase in systematic reviews of …
increased considerably in recent years, with a subsequent increase in systematic reviews of …
Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians
Mendelian randomisation uses genetic variation as a natural experiment to investigate the
causal relations between potentially modifiable risk factors and health outcomes in …
causal relations between potentially modifiable risk factors and health outcomes in …
Using Mendelian randomisation to assess causality in observational studies
Objective Mendelian randomisation (MR) is a technique that aims to assess causal effects of
exposures on disease outcomes. The paper aims to present the main assumptions that …
exposures on disease outcomes. The paper aims to present the main assumptions that …
Nature as a trialist?: deconstructing the analogy between Mendelian randomization and randomized trials
Mendelian randomization (MR) studies are often described as naturally occurring
randomized trials in which genetic factors are randomly assigned by nature …
randomized trials in which genetic factors are randomly assigned by nature …
An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings
E Sanderson, G Davey Smith… - International journal …, 2019 - academic.oup.com
Background Mendelian randomization (MR) is a powerful tool in epidemiology that can be
used to estimate the causal effect of an exposure on an outcome in the presence of …
used to estimate the causal effect of an exposure on an outcome in the presence of …
Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review
Diseases diagnosed in adulthood may have antecedents throughout (including prenatal)
life. Gaining a better understanding of how exposures at different stages in the lifecourse …
life. Gaining a better understanding of how exposures at different stages in the lifecourse …
MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data
OO Yavorska, S Burgess - International journal of epidemiology, 2017 - academic.oup.com
MendelianRandomization is a software package for the R open-source software
environment that performs Mendelian randomization analyses using summarized data. The …
environment that performs Mendelian randomization analyses using summarized data. The …