Pathogenesis of pituitary tumors
S Melmed - Nature Reviews Endocrinology, 2011 - nature.com
Pituitary adenomas may hypersecrete hormones (including prolactin, growth hormone and
adrenocorticotropic hormone, and rarely follicle-stimulating hormone, luteinizing hormone or …
adrenocorticotropic hormone, and rarely follicle-stimulating hormone, luteinizing hormone or …
The pathogenesis of pituitary tumors
Recently there has been significant progress in our understanding of pituitary development,
physiology, and pathology. New information has helped to clarify the classification of …
physiology, and pathology. New information has helped to clarify the classification of …
Mechanisms of disease: the pathogenesis of pituitary tumors
Pituitary tumors exhibit a spectrum of biology, with variable growth and hormonal behaviors.
They therefore provide an opportunity to examine pathogenetic mechanisms that underlie …
They therefore provide an opportunity to examine pathogenetic mechanisms that underlie …
Pituitary tumor pathogenesis
I Shimon, S Melmed - The Journal of Clinical Endocrinology & …, 1997 - academic.oup.com
Pituitary tumors are mostly benign monoclonal adenomas arising from adenohypophyseal
cells in the anterior pituitary. These tumors usually autonomously express and secrete …
cells in the anterior pituitary. These tumors usually autonomously express and secrete …
Molecular pathogenesis of pituitary tumors
WE Farrell, RN Clayton - Frontiers in neuroendocrinology, 2000 - Elsevier
Pituitary tumors are the result of a monoclonal outgrowth where the intrinsic genetic defects
involve oncogenes, tumor suppressor genes (TSG), and most likely genes responsible for …
involve oncogenes, tumor suppressor genes (TSG), and most likely genes responsible for …
Clinical biology of the pituitary adenoma
S Melmed, UB Kaiser, MB Lopes, J Bertherat… - Endocrine …, 2022 - academic.oup.com
All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …
Novel insights into pituitary tumorigenesis: genetic and epigenetic mechanisms
V Srirangam Nadhamuni, M Korbonits - Endocrine reviews, 2020 - academic.oup.com
Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …
Similar to many other endocrine tumors, over the last few years we have recognized the role …
[HTML][HTML] Pituitary tumors
S Melmed - Endocrinology and metabolism clinics of North America, 2015 - ncbi.nlm.nih.gov
Anterior pituitary cell types express distinct hormone gene products. These include ACTH,
GH, PRL, TSH, FSH and LH. Pituitary adenomas are distinguished by both excess …
GH, PRL, TSH, FSH and LH. Pituitary adenomas are distinguished by both excess …
[PDF][PDF] Pituitary tumours
JRE Davis, WE Farrell, RN Clayton - 1999 - pdfs.semanticscholar.org
Pituitary tumours are a common type of intracranial neoplasm and, depending on the cell
type of origin, have diverse endocrine and reproductive effects. The developmental biology …
type of origin, have diverse endocrine and reproductive effects. The developmental biology …