Metabolic labeling of glycans with clickable unnatural sugars has enabled glycan analysis in
multicellular systems. However, cell-type-specific labeling of glycans in vivo remains …

In the heart, glycosylation is involved in a variety of physiological and pathological
processes. Cardiac glycosylation is dynamically regulated, which remains challenging to …

Since the pioneering work by Reutter and co‐workers that demonstrated structural flexibility
in the carbohydrate biosynthesis and glycosylation pathways, many different labs have used …

Metabolic labeling of glycans with a bioorthogonal chemical reporter such as the azide
enables their visualization in cells and organisms as well as the enrichment of specific …

Metabolic labeling of glycans with synthetic sugar analogs has emerged as an attractive
means for introducing nonnatural chemical functionality into glycoproteins. However, the …

The study of cellular glycosylation presents many challenges due, in large part, to the
nontemplated nature of glycan biosynthesis and glycans' structural complexity …

Cell surface glycoproteins play critical roles in maintaining cardiac structure and function in
health and disease and the glycan-moiety attached to the protein is critical for proper protein …

Glycans can be directly labeled using unnatural monosaccharide analogs, termed metabolic
chemical reporters (MCRs). These compounds enable the secondary visualization and …

The glycocalyx comprises glycosylated proteins and lipids and fcorms the outermost layer of
cells. It is involved in fundamental inter-and intracellular processes, including non-self-cell …

The new field of functional glycomics encompasses information about both glycan structure
and recognition by carbohydrate-binding proteins (CBPs) and is now being explored …