Differential activation of programmed cell death in patients with severe SARS-CoV-2 infection

AN Riegler, P Benson, K Long, SM Leal Jr - Cell Death Discovery, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe lower
airway disease and death in a subset of patients. Knowledge on the relative contribution of …

A confusion of pathways: Discerning cell death mechanisms in SARS-CoV-2 infection

LYR Wong, S Perlman - Science immunology, 2024 - science.org
A confusion of pathways: Discerning cell death mechanisms in SARS-CoV-2 infection | Science
Immunology news careers commentary Journals Science Science brought to you byGoogle …

SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

AC Ferreira, VC Soares… - Cell death …, 2021 - nature.com
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
associated with leukopenia and uncontrolled inflammatory response in critically ill patients …

The role of cell death in SARS-CoV-2 infection

C Yuan, Z Ma, J Xie, W Li, L Su, G Zhang, J Xu… - Signal transduction and …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …

[HTML][HTML] Pyroptotic cell death in SARS-CoV-2 infection: revealing its roles during the immunopathogenesis of COVID-19

M Wang, W Chang, L Zhang… - International Journal of …, 2022 - ncbi.nlm.nih.gov
The rapid dissemination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
the causative agent of coronavirus disease 2019 (COVID-19), remains a global public health …

Cell-type apoptosis in lung during SARS-CoV-2 infection

Y Liu, TM Garron, Q Chang, Z Su, C Zhou, Y Qiu… - Pathogens, 2021 - mdpi.com
The SARS-CoV-2 pandemic has inspired renewed interest in understanding the
fundamental pathology of acute respiratory distress syndrome (ARDS) following infection …

Cell death in coronavirus infections: Uncovering its role during COVID-19

A Paolini, R Borella, S De Biasi, A Neroni, M Mattioli… - Cells, 2021 - mdpi.com
Cell death mechanisms are crucial to maintain an appropriate environment for the
functionality of healthy cells. However, during viral infections, dysregulation of these …

Therapy targets SARS-CoV-2 infection-induced cell death

Z Zhu, J Shi, L Li, J Wang, Y Zhao, H Ma - Frontiers in Immunology, 2022 - frontiersin.org
Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV-2 has become a global
health issue. The clinical presentation of COVID-19 is highly variable, ranging from …

SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation

S Li, Y Zhang, Z Guan, H Li, M Ye, X Chen… - Signal transduction and …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can lead to
respiratory illness and multi-organ failure in critically ill patients. Although the virus-induced …

Unveiling the Pathological Mechanisms of Death Induced by SARS-CoV-2 Viral Pneumonia

GC Oprinca, CI Mohor, A Oprinca-Muja, A Hașegan… - Microorganisms, 2024 - mdpi.com
In this comprehensive study of 15 deceased patients with confirmed SARS-CoV-2 infection,
spanning a time frame of 1 to 68 days from confirmation to death, autopsies were …