Colorectal dysplasia in chronic inflammatory bowel disease: pathology, clinical implications, and pathogenesis

N Harpaz, AD Polydorides - Archives of pathology & …, 2010 - meridian.allenpress.com
Context.—Colorectal cancer, the most lethal long-term complication of chronic inflammatory
bowel disease (IBD), is the culmination of a complex sequence of molecular and histologic …

Dysplastic lesions in inflammatory bowel disease: molecular pathogenesis to morphology

KA Matkowskyj, ZE Chen, MS Rao… - Archives of pathology …, 2013 - meridian.allenpress.com
Context.—Inflammatory bowel disease (IBD) is a long-standing chronic active inflammatory
process in the bowel with increased risk for the development of colorectal carcinoma …

Colorectal dysplasia in chronic inflammatory bowel disease: a contemporary consensus classification and interobserver study

N Harpaz, JR Goldblum, NA Shepherd, RH Riddell… - Human Pathology, 2023 - Elsevier
The clinical management of patients with dysplasia in chronic inflammatory bowel disease
(IBD) is currently guided by Riddell et al.'s grading system (negative, indefinite, low grade …

Colorectal cancer in idiopathic inflammatory bowel disease.

N Harpaz, IC Talbot - Seminars in diagnostic pathology, 1996 - europepmc.org
The development of colorectal cancer is the most serious long-term problem faced by
patients with extensive ulcerative colitis and Crohn's colitis, with an incidence 20-fold higher …

[HTML][HTML] Microscopic features of colorectal neoplasia in inflammatory bowel diseases

A Bressenot, V Cahn, S Danese… - World Journal of …, 2014 - ncbi.nlm.nih.gov
The risk of developing dysplasia leading to colorectal cancer (CRC) is increased in both
ulcerative colitis and Crohn's disease. The prognosis of CRC may be poorer in patients with …

Dysplasia in inflammatory bowel disease: historical review, critical histopathological analysis, and clinical implications

A Mark-Christensen, S Laurberg… - Inflammatory Bowel …, 2018 - academic.oup.com
Colorectal cancer is the most serious complication of chronic inflammatory bowel disease. It
is generally accepted that dysplasia in most cases precedes the development of colorectal …

Colorectal dysplasia in inflammatory bowel disease: a clinicopathologic perspective

MD Rutter, RH Riddell - Clinical Gastroenterology and Hepatology, 2014 - Elsevier
Surveillance for neoplasia in colitis is the most challenging diagnostic colonoscopic
procedure. The detection and treatment of colorectal dysplasia in inflammatory bowel …

Pathology of dysplasia and cancer in inflammatory bowel disease

RD Odze - Gastroenterology Clinics, 2006 - gastro.theclinics.com
In ulcerative colitis (UC) and Crohn's disease (CD), there is abundant evi-dence to support
the theory that cancer develops through an inflammation-dysplasia-carcinoma sequence [1 …

Precancerous lesions in inflammatory bowel disease

N Harpaz, SC Ward, C Mescoli, SH Itzkowitz… - Best practice & research …, 2013 - Elsevier
Reduction of mortality from colorectal cancer is a prime goal in the clinical management of
patients with extensive, longstanding ulcerative colitis and colonic Crohn's disease. The …

[HTML][HTML] Colorectal cancer and dysplasia in inflammatory bowel disease

TL Zisman, DT Rubin - World journal of gastroenterology: WJG, 2008 - ncbi.nlm.nih.gov
Both ulcerative colitis and Crohn's disease carry an increased risk of developing colorectal
cancer. Established risk factors for cancer among patients with inflammatory bowel disease …