The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress
Review Group meeting of the National Institute of Neurological Disorders and Stroke …

Over the past 10 years, study of the blood vessel in cerebrovascular disease has expanded
from consideration of only endothelial cells to include interactions with neurons, astrocytes …

Pathophysiology of the neurovascular unit (NVU) is commonly seen in neurological
diseases. The typical features of NVU pathophysiology include tissue hypoxia, inflammatory …

Formulated as a group effort of the stroke community, the transforming concept of the
neurovascular unit (NVU) depicts the structural and functional relationship between brain …

Components of the neurovascular unit (NVU) establish dynamic crosstalk that regulates
cerebral blood flow and maintain brain homeostasis. Here, we describe accumulating …

Current understanding on the mechanisms of brain injury and neurodegeneration highlights
an appreciation of multicellular interactions within the neurovascular unit (NVU), which …

In the past decade, evidence has emerged that there is a variety of bidirectional cell-cell
and/or cellextracellular matrix interactions within the neurovascular unit (NVU), which is …

Ischaemic stroke is a leading cause of disability and death for which no acute treatments
exist beyond recanalization. The development of novel therapies has been repeatedly …

Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …

The concept of the neurovascular unit as the key brain component affected by stroke is
controversial, because current definitions of this entity neglect mechanisms that control …