The article provides information on cystic fibrosis (CF) including survival trends, disease
variability and future treatment choices. CF refers to a genetic disorder that has a …

Cystic fibrosis (CF) is an autosomal recessive, multisystem disorder which greatly reduces
the lifespan of its victims, largely by gradual, infection-driven destruction of the lungs …

Cystic fibrosis (CF) was distinguished from celiac disease in 1938. Then, it was a pathologic
diagnosis, life expectancy was approximately 6 months, and the autosomal recessive …

The median estimated life expectancy of children with cystic fibrosis (CF) born in 1990 is 40
years which represents a doubling in the last 20 years, and nearly half of all patients are …

Cystic fibrosis (CF) has received considerable public attention since the mid 1980s, when
researchers began closing in on the identification of the CF gene. With the gene isolation in …

Improvements in outcomes for patients who have cystic fibrosis (CF) have been striking in
the last 30 years. Median survival now approaches the fifth decade of life. Advances in the …

Cystic fibrosis (CF) is the most common life-limiting inherited illness of whites. Most of the
morbidity and mortality in CF stems from impaired mucociliary clearance leading to chronic …

Cystic fibrosis used to be thought of as a respiratory and digestive disease, with a uniformly
and rapidly fatal outcome. The spectrum of the disease has broadened into the mild atypical …

The pulmonary involvement in cystic fibrosis (CF) is discussed from several perspectives
including historical, current treatment, and possible future therapies. The clinical realities …

Cystic fibrosis is an inherited disease affecting mainly the Caucasian population. In recent
years there have been major advances in understanding the genetics and pathophysiology …