[HTML][HTML] Shared and distinct transcriptomic cell types across neocortical areas
The neocortex contains a multitude of cell types that are segregated into layers and
functionally distinct areas. To investigate the diversity of cell types across the mouse …
functionally distinct areas. To investigate the diversity of cell types across the mouse …
[HTML][HTML] Single-cell delineation of lineage and genetic identity in the mouse brain
During neurogenesis, mitotic progenitor cells lining the ventricles of the embryonic mouse
brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic …
brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic …
Conserved cell types with divergent features in human versus mouse cortex
Elucidating the cellular architecture of the human cerebral cortex is central to understanding
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA …
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA …
[HTML][HTML] Phenotypic variation of transcriptomic cell types in mouse motor cortex
Cortical neurons exhibit extreme diversity in gene expression as well as in morphological
and electrophysiological properties 1, 2. Most existing neural taxonomies are based on …
and electrophysiological properties 1, 2. Most existing neural taxonomies are based on …
Human neocortical expansion involves glutamatergic neuron diversification
The neocortex is disproportionately expanded in human compared with mouse,, both in its
total volume relative to subcortical structures and in the proportion occupied by …
total volume relative to subcortical structures and in the proportion occupied by …
Individual human cortical progenitors can produce excitatory and inhibitory neurons
The cerebral cortex is a cellularly complex structure comprising a rich diversity of neuronal
and glial cell types. Cortical neurons can be broadly categorized into two classes …
and glial cell types. Cortical neurons can be broadly categorized into two classes …
[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …
types with specific spatial distribution patterns and structural and functional properties …
A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased
samples of the diverse cell types in the brain,–. With the proliferation of multi-omics datasets …
samples of the diverse cell types in the brain,–. With the proliferation of multi-omics datasets …
Molecular logic of cellular diversification in the mouse cerebral cortex
The mammalian cerebral cortex has an unparalleled diversity of cell types, which are
generated during development through a series of temporally orchestrated events that are …
generated during development through a series of temporally orchestrated events that are …
Epigenomic diversity of cortical projection neurons in the mouse brain
Neuronal cell types are classically defined by their molecular properties, anatomy and
functions. Although recent advances in single-cell genomics have led to high-resolution …
functions. Although recent advances in single-cell genomics have led to high-resolution …