In vitro cytotoxicity and interaction of noscapine with human serum albumin: Effect on structure and esterase activity of HSA

N Maurya, JK Maurya, UK Singh, R Dohare… - Molecular …, 2019 - ACS Publications
Noscapine is effective to inhibit cellular proliferation and induced apoptosis in nonsmall cell,
lung, breast, lymphoma, and prostate cancer. It also shows good efficiency to skin cancer …

Interaction of noscapine with human serum albumin (HSA): A spectroscopic and molecular modelling approach

H Chugh, P Kumar, V Tomar, N Kaur, D Sood… - … of Photochemistry and …, 2019 - Elsevier
Noscapine hydrochloride (Nos), an opium derived anticancer agent manifests therapeutic
applications and is compliant to beneficial modifications. In this paper, we study its …

Interactions between epinastine and human serum albumin: Investigation by fluorescence, UV–vis, FT–IR, CD, lifetime measurement and molecular docking

GG Ariga, PN Naik, SA Chimatadar… - Journal of Molecular …, 2017 - Elsevier
The fluorescence quenching of human serum albumin (HSA) by epinastine hydrochloride
(EPN) at pH 7.4 buffer was studied using absorption, fluorescence quenching, time …

Mechanistic interaction study of bromo-noscapine with bovine serum albumin employing spectroscopic and chemoinformatics approaches

D Sood, N Kumar, G Rathee, A Singh, V Tomar… - Scientific Reports, 2018 - nature.com
Abstract Bromo-Noscapine (BrNs) is a tubulin-binding cytotoxic agent with significant activity
against breast and lung cancer. The mechanistic interaction insight into the binding of …

Binding of tolperisone hydrochloride with human serum albumin: effects on the conformation, thermodynamics, and activity of HSA

G Rabbani, EJ Lee, K Ahmad, MH Baig… - Molecular …, 2018 - ACS Publications
Tolperisone hydrochloride (TH) has muscle relaxant activity and has been widely used for
several years in clinical practice to treat pathologically high skeletal muscle tone (spasticity) …

[HTML][HTML] Spectroscopic study on the interaction between mononaphthalimide spermidine (MINS) and bovine serum albumin (BSA)

Z Tian, F Zang, W Luo, Z Zhao, Y Wang, X Xu… - … of Photochemistry and …, 2015 - Elsevier
The interaction mononaphthalimide spermidine (MINS, 1) and bovine serum albumin (BSA)
was studied by UV/vis absorption, fluorescence and circular dichroism spectra (CD) under …

Elucidating the binding propensity of naphthyl hydroxamic acid to human serum albumin (HSA): multi-spectroscopic and molecular modeling approach

R Agrawal, Y Thakur, M Tripathi, MK Siddiqi… - Journal of Molecular …, 2019 - Elsevier
The association of human serum albumin (HSA) and its interaction with drug and other novel
compound has garnered keen interest in designing and development for new compounds …

Deciphering the binding mechanism of noscapine with lysozyme: biophysical and chemoinformatic approaches

D Sood, N Kumar, A Singh, V Tomar, SK Dass… - ACS …, 2019 - ACS Publications
Lysozyme is a well-characterized protein in terms of its structure, dynamics, and functions. It
has thus emerged as a potential target to understand protein–drug interactions. The aim of …

Biophysical study on the interaction between eperisone hydrochloride and human serum albumin using spectroscopic, calorimetric, and molecular docking analyses

G Rabbani, MH Baig, EJ Lee, WK Cho… - Molecular …, 2017 - ACS Publications
Eperisone hydrochloride (EH) is widely used as a muscle relaxant for patients with muscular
contracture, low back pain, or spasticity. Human serum albumin (HSA) is a highly soluble …

Cytotoxicity and comparative binding mechanism of piperine with human serum albumin and α-1-acid glycoprotein

DP Yeggoni, A Rachamallu, M Kallubai… - Journal of …, 2015 - Taylor & Francis
Human serum albumin (HSA) and α-1-acid glycoprotein (AGP)(acute phase protein) are the
plasma proteins in blood system which transports many drugs. To understand the …