Emerging from the origins of supramolecular chemistry and the development of selective
chemical receptors that rely on lock‐and‐key binding, activity‐based sensing (ABS)—which …

In contrast to the classical design of a probe with one binding site to target one specific
analyte, probes with multiple interaction sites or, alternatively, with single sites promoting …

Traditional analyte-specific synthetic receptors or sensors have been developed on the
basis of supramolecular interactions (eg, hydrogen bonding, electrostatics, weak …

The complex network of chemical processes that sustain life motivates the development of
new synthetic tools to decipher biological mechanisms of action at a molecular level. In this …

Conspectus Reactivity-based organic bioprobes have been increasingly designed and
developed in the last couple of years to address important questions in numerous fields …

Since as early as 1867, molecular sensors have been recognized as being intelligent
“devices” capable of addressing a variety of issues related to our environment and health …

The dynamic chemical diversity of elements, ions and molecules that form the basis of life
offers both a challenge and an opportunity for study. Small-molecule fluorescent probes can …

Conspectus Fluorescent sensing has emerged as a powerful tool for detecting various
analytes and visualizing numerous biological processes by virtue of its superb sensitivity …

Conspectus The promising features of fluorescence spectroscopy have inspired a quest for
fluorescent probes for analysis and monitoring of molecular interactions in biochemical …

Small-molecule based fluorescent probes are increasingly important for the detection and
imaging of biological signaling molecules due to their simplicity, high selectivity and …