[HTML][HTML] Strategies to overcome DC dysregulation in the tumor microenvironment
G Mestrallet, K Sone, N Bhardwaj - Frontiers in Immunology, 2022 - frontiersin.org
Dendritic cells (DCs) play a key role to modulate anti-cancer immunity in the tumor
microenvironment (TME). They link innate to adaptive immunity by processing and …
microenvironment (TME). They link innate to adaptive immunity by processing and …
[HTML][HTML] Impaired function of dendritic cells within the tumor microenvironment
Z Xiao, R Wang, X Wang, H Yang, J Dong… - Frontiers in …, 2023 - frontiersin.org
Dendritic cells (DCs), a class of professional antigen-presenting cells, are considered key
factors in the initiation and maintenance of anti-tumor immunity due to their powerful ability …
factors in the initiation and maintenance of anti-tumor immunity due to their powerful ability …
Molecular mechanisms involved in dendritic cell dysfunction in cancer
M Tang, J Diao, MS Cattral - Cellular and Molecular Life Sciences, 2017 - Springer
Dendritic cells (DC) play a pivotal role in the tumor microenvironment (TME). As the primary
antigen-presenting cells in the tumor, DCs modulate anti-tumor responses by regulating the …
antigen-presenting cells in the tumor, DCs modulate anti-tumor responses by regulating the …
Tumor microenvironment-related dendritic cell deficiency: a target to enhance tumor immunotherapy
S Zhu, N Yang, J Wu, X Wang, W Wang, YJ Liu… - Pharmacological …, 2020 - Elsevier
Dendritic cells (DCs), as specialized antigen-presenting cells, are essential for the initiation
of specific T cell responses in innate antitumor immunity and, in certain cases, support …
of specific T cell responses in innate antitumor immunity and, in certain cases, support …
[HTML][HTML] Pathological mobilization and activities of dendritic cells in tumor-bearing hosts: challenges and opportunities for immunotherapy of cancer
AJ Tesone, N Svoronos, MJ Allegrezza… - Frontiers in …, 2013 - frontiersin.org
A common characteristic of solid tumors is the pathological recruitment of
immunosuppressive myeloid cells, which in certain tumors includes dendritic cells (DCs) …
immunosuppressive myeloid cells, which in certain tumors includes dendritic cells (DCs) …
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): a novel population in the tumour microenvironment and immunotherapy target
J Li, J Zhou, H Huang, J Jiang… - Clinical and …, 2023 - Wiley Online Library
Abstract Background Dendritic cells (DCs) mediate divergent immune effects by activating T
cells or negatively regulating the immune response to promote immune tolerance. They …
cells or negatively regulating the immune response to promote immune tolerance. They …
[HTML][HTML] Dendritic cells and cancer: from biology to therapeutic intervention
Inducing effective anti-tumor immunity has become a major therapeutic strategy against
cancer. Dendritic cells (DC) are a heterogenous population of antigen presenting cells that …
cancer. Dendritic cells (DC) are a heterogenous population of antigen presenting cells that …
[HTML][HTML] Tumor-infiltrating dendritic cells: decisive roles in cancer immunosurveillance, immunoediting, and tumor T cell tolerance
T Katopodi, S Petanidis, C Charalampidis… - Cells, 2022 - mdpi.com
The tumor microenvironment plays a key role in progression of tumorigenesis, tumor
progression, and metastasis. Accumulating data reveal that dendritic cells (DCs) appear to …
progression, and metastasis. Accumulating data reveal that dendritic cells (DCs) appear to …
[HTML][HTML] Deciphering tumor-infiltrating dendritic cells in the single-cell era
Q Huang, F Wang, D Hao, X Li, X Li, T Lei… - … Hematology & Oncology, 2023 - Springer
Dendritic cells (DCs) serve as a pivotal link connecting innate and adaptive immunity by
processing tumor-derived antigens and activating T cells. The advent of single-cell …
processing tumor-derived antigens and activating T cells. The advent of single-cell …
[HTML][HTML] Dendritic cell subsets in cancer immunity and tumor antigen sensing
Dendritic cells (DCs) exhibit a specialized antigen-presenting function and play crucial roles
in both innate and adaptive immune responses. Due to their ability to cross-present tumor …
in both innate and adaptive immune responses. Due to their ability to cross-present tumor …