The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

The placenta is a remarkable organ. In normal pregnancy its specialized cells (termed
cytotrophoblasts) differentiate into various specialized subpopulations that play pivotal roles …

BACKGROUND: Preeclampsia is a pregnancy-specific disorder that remains a leading
cause of maternal, fetal and neonatal morbidity and mortality, and is associated with risk for …

Background: The pregnancy pathology preeclampsia is still among the leading causes of
maternal and perinatal morbidity and mortality. At the same time, its etiology is far from being …

The human placenta is a poorly-understood organ, but one that is critical for proper
development and growth of the fetus in-utero. The epithelial cell type that contributes to …

In preeclampsia, as a heterogeneous syndrome, multiple pathways have been proposed for
both the causal as well as the perpetuating factors leading to maternal vascular dysfunction …

Preeclampsia, which manifests itself as hypertension, proteinuria, and edema in pregnancy,
requires the presence of trophoblast tissue but not a fetus. It is characterized by abnormal …

We investigated the global placental gene expression profile in severe preeclampsia.
Twenty-one women were randomly selected from 50 participants with uncomplicated …

Pre-eclampsia is a multisystem disorder with profound implications for both mother and
fetus. Its origins lie in the earliest stages of pregnancy. Abnormal interactions between fetal …

Background The maternal signs of preeclampsia, which include the new onset of high blood
pressure, can occur because of faulty placentation. We theorized that transcriptomic …