Effectiveness of dupilumab in pediatric patients with a nummular phenotype of atopic dermatitis

EJ Kim, M Hlobik, T Ho - Pediatric Dermatology, 2024 - Wiley Online Library
The nummular phenotype of atopic dermatitis is clinically characterized by pruritic, coin‐
shaped plaques that are frequently recalcitrant to treatment. In this study, a retrospective …

Dupilumab provides rapid improvement for morphologic variants of paediatric atopic dermatitis: A case series

JW Kim, M Kim, GS Ahn, J Im Na - Indian Journal of Dermatology …, 2022 - ijdvl.com
The results from our dupilumab study in paediatric atopic dermatitis patients with nummular
eczema and prurigonodularis phenotypes are consistent with previous findings in adult …

Dupilumab Provides Clinically Meaningful Responses in Children Aged 6–11 Years with Severe Atopic Dermatitis: Post Hoc Analysis Results from a Phase III Trial

EC Siegfried, MJ Cork, N Katoh, H Zhang… - American Journal of …, 2023 - Springer
Background Children with severe atopic dermatitis (AD) have a multidimensional disease
burden. Objective Here we assess the clinically meaningful improvements in AD signs …

Psoriasiform dermatitis during dupilumab treatment for moderate‐to‐severe atopic dermatitis in children

JJ Parker, JL Sugarman, NB Silverberg… - Pediatric …, 2021 - Wiley Online Library
Abstract Background/Objectives Psoriasiform eruptions after initiation of dupilumab have
been previously described in adults. This report details the risk of developing or unmasking …

Angioedema: a potential complication of dupilumab in atopic dermatitis

AL Fritz, FA Lacy, DS Morrell - Pediatric Dermatology, 2021 - Wiley Online Library
Dupilumab is a relatively new and quite effective medication for recalcitrant atopic dermatitis
in patients over 6 years of age. Here, we present a 12‐year‐old girl with progressively …

Dupilumab Safety and Efficacy in a Phase III Open-Label Extension Trial in Children 6–11 Years of Age with Severe Atopic Dermatitis

MJ Cork, D Thaçi, LF Eichenfield, PD Arkwright… - Dermatology and …, 2023 - Springer
Background For children aged 6–11 years with uncontrolled severe atopic dermatitis (AD),
16 weeks of treatment with dupilumab resulted in substantial clinical benefit compared with …

Use of dupilimab in pediatric atopic dermatitis: access, dosing, and implications for managing severe atopic dermatitis

EC Siegfried, S Igelman, JC Jaworsk… - Pediatric …, 2019 - Wiley Online Library
The recent US Food and Drug Administration (FDA) approval of dupilumab for atopic
dermatitis (AD) has heralded “the decade of eczema,” but it may take several more years …

Effectiveness and safety of dupilumab in children under 6 years of age with moderate-to-severe atopic dermatitis: a retrospective real-world study

E Berna-Rico, E Fiz-Benito, JM Busto-Leis… - Dermatology, 2024 - karger.com
Introduction: Dupilumab has recently been shown to be effective in children under 6 years of
age with atopic dermatitis (AD). Nevertheless, real-life and long-term follow-up data are …

Dupilumab Safety and Efficacy up to 1 Year in Children Aged 6 Months to 5 Years with Atopic Dermatitis: Results from a Phase 3 Open-Label Extension Study

AS Paller, EC Siegfried, EL Simpson, MJ Cork… - American Journal of …, 2024 - Springer
Background Pediatric patients with moderate-to-severe atopic dermatitis (AD) often
experience a high disease burden and have a high risk of persistent disease. Standard-of …

Long‐term off‐label dupilumab in pediatric atopic dermatitis: a case series

AD Treister, PA Lio - Pediatric dermatology, 2019 - Wiley Online Library
Abstract Background/Objectives Clinical trials of dupilumab have shown efficacy in treating
moderate‐to‐severe atopic dermatitis (AD) in adult patients. While a phase 2 trial of …