Cerebral small vessel disease (SVD) is a major cause of stroke and dementia. The
underlying pathogenesis is poorly understood, but both neuroinflammation and increased …

Abstract Background and Aim: Dilated perivascular spaces (dPVS) have previously been
associated with aging and hypertension-related cerebral microangiopathy. However, their …

Dementia is a global growing concern, affecting over 35 million people with a global
economic impact of over $604 billion US. With an ageing population the number of people …

Cerebral small vessel disease (SVD) is a major cause of age-related cognitive impairment
and dementia. The pathophysiology of SVD is not well understood and is hampered by a …

Cerebral small vessel disease (SVD) is highly prevalent and a common cause of ischemic
and hemorrhagic stroke and dementia, yet the pathophysiology is poorly understood. Its …

Objective Cerebral small vessel diseases (cSVDs) are a major cause of stroke and
dementia. We used cutting‐edge 7T‐MRI techniques in patients with Cerebral Autosomal …

Objectives: Cerebral small vessel disease (SVD) is common in aged brains and causes
lacunar stroke, diffuse white matter lesions (leukoaraiosis), and vascular cognitive …

Background and aim The pathogenesis of cerebral small-vessel disease (SVD) is
incompletely understood. Endothelial dysfunction has been implicated and may result in …

Dementia is a major social and economic problem for our aging population. One of the most
common of dementia in the elderly is cerebral small vessel disease (SVD). Magnetic …

Background and Purpose—Increased blood–brain barrier (BBB) permeability occurs in
cerebral small vessel disease. It is not known if BBB changes predate progression of small …