The newly evolved gene Heterochromatin Protein 6 (HP6), which has been previously
classified as essential, challenged the dogma that functions required for viability are only …

Heterochromatin is the gene-poor, satellite-rich eukaryotic genome compartment that
supports many essential cellular processes. The functional diversity of proteins that bind and …

Heterochromatin is the gene-poor, transposon-rich, late-replicating chromatin compartment
that was first cytologically defined more than 70 years ago. The identification of …

In Drosophila melanogaster, primordial germ cells are specified at the posterior pole of the
very early embryo. This process is regulated by the posterior localized germ plasm that …

Heterochromatin protein 1a (HP1a) is a highly conserved and versatile epigenetic factor that
can both silence and activate transcription. However, the function of HP1a in development …

Heterochromatin comprises a significant component of many eukaryotic genomes. In
comparison to euchromatin, heterochromatin is gene poor, transposon rich, and late …

Heterochromatin protein 1 (HP1) proteins are conserved in eukaryotes, with most species
containing several isoforms. Based on the properties of Drosophila HP1a, it was proposed …

Abstract Heterochromatin protein 1 (HP1) is a non-histone chromosomal protein first
identified in Drosophila as a major component of constitutive heterochromatin, required for …

Stem cell maintenance requires expression of genes essential for stemness and repression
of differentiation genes. How this is achieved remains incompletely understood. Here we …

A key aspect of germ cell development is to establish germline sexual identity and initiate a
sex-specific developmental program to promote spermatogenesis or oogenesis. Previously …