Objectives: To determine factors associated with disease‐free survival (DFS) and regional
control in clinically node‐negative head and neck squamous cell cancer (HNSCC) patients …

There is a large body of evidence in the European and US literature which argues forcefully
that the presence of metastatic deposits within cervical lymph nodes is the single most …

Background: The management of the N0 neck in oral and oropharyngeal cancer is often
determined by the risk of metastases related to features of the primary tumor. Where the risk …

Incidence of isolated distant metastasis (IDM) was relatively low in patients who achieved
locoregional control after primary definitive surgery. However, the prognosis of patients with …

Objective. Head and neck squamous cell carcinoma (HNSCC) patients with N3 neck
disease at presentation are the minority. Prognosis for such patients is poor, but there is …

Abstract Objectives/Hypothesis: Management of the N0 neck is a continuing controversy.
The study compares the influence of N0 and N+ disease on the results of treating squamous …

Background The recognition of patients at high risk for the development of distant metastasis
(DM) is required to recognize a subset of patients who may benefit from systemic therapy …

Objectives Management of the neck in patients with oral squamous cell carcinoma (OSCC)
is pivotal to oncologic control and survival. However, there is controversy regarding …

Background One of the reasons for failure in patients with head and neck carcinoma who
achieve locoregional control with treatment is the appearance of distant metastases. The …

Background. The incidence of distant metastases in head and neck cancer patients is rising
because of greater locoregional control of the disease. Methods. The relative risks for having …