In the past decades, apoptosis has been the most well-studied regulated cell death (RCD)
that has essential functions in tissue homeostasis throughout life. However, a novel form of …

Necroptosis is generally considered as an inflammatory cell death form. The core regulators
of necroptotic signaling are receptor‐interacting serine–threonine protein kinases 1 (RIPK1) …

By regulating the cell number and eliminating harmful cells, programmed cell death plays a
critical role in development, homeostasis, and disease. While apoptosis is a recognized form …

Necroptosis is a genetically regulated form of necrotic cell death that has emerged as an
important pathway in human disease. The necroptosis pathway is induced by a variety of …

Necroptosis is a form of programmed necrosis that is mediated by various cytokines and
pattern recognition receptors (PRRs). Cells dying by necroptosis show necrotic phenotypes …

Rationale: Necroptosis, mediated by RIPK3 (receptor-interacting protein kinase 3) and
MLKL (mixed lineage kinase domain-like), is a form of regulated necrosis that can drive …

Programmed cell death plays an important role in maintaining homeostasis. Necroptosis is a
type of programmed cell death that has been recently discovered. It is mediated by RIPK1 …

Pneumonia remains a major global health challenge, necessitating the development of
effective therapeutic approaches. Recently, necroptosis, a regulated form of cell death, has …

Cell death is increasingly recognized as a driving factor in the development of acute lung
injury. Necroptosis, an immunogenic regulated cell death program important in innate …

A newly discovered mechanism of cell death, programmed necrosis (necroptosis), combines
features of both necrosis and apoptosis. Necroptosis is tightly modulated by a series of …