Necroptosis in pulmonary diseases: a new therapeutic target
L Wang, L Zhou, Y Zhou, L Liu, W Jiang… - Frontiers in …, 2021 - frontiersin.org
In the past decades, apoptosis has been the most well-studied regulated cell death (RCD)
that has essential functions in tissue homeostasis throughout life. However, a novel form of …
that has essential functions in tissue homeostasis throughout life. However, a novel form of …
Cell type‐specific molecular mechanisms and implications of necroptosis in inflammatory respiratory diseases
Y Guo, J Zhou, Y Wang, X Wu, Y Mou… - Immunological …, 2024 - Wiley Online Library
Necroptosis is generally considered as an inflammatory cell death form. The core regulators
of necroptotic signaling are receptor‐interacting serine–threonine protein kinases 1 (RIPK1) …
of necroptotic signaling are receptor‐interacting serine–threonine protein kinases 1 (RIPK1) …
The role of necroptosis in pulmonary diseases
K Mizumura, S Maruoka, Y Gon, AMK Choi… - Respiratory …, 2016 - Elsevier
By regulating the cell number and eliminating harmful cells, programmed cell death plays a
critical role in development, homeostasis, and disease. While apoptosis is a recognized form …
critical role in development, homeostasis, and disease. While apoptosis is a recognized form …
[HTML][HTML] Necroptosis: a crucial pathogenic mediator of human disease
ME Choi, DR Price, SW Ryter, AMK Choi - JCI insight, 2019 - ncbi.nlm.nih.gov
Necroptosis is a genetically regulated form of necrotic cell death that has emerged as an
important pathway in human disease. The necroptosis pathway is induced by a variety of …
important pathway in human disease. The necroptosis pathway is induced by a variety of …
Necroptosis molecular mechanisms: Recent findings regarding novel necroptosis regulators
Necroptosis is a form of programmed necrosis that is mediated by various cytokines and
pattern recognition receptors (PRRs). Cells dying by necroptosis show necrotic phenotypes …
pattern recognition receptors (PRRs). Cells dying by necroptosis show necrotic phenotypes …
Necroptosis signaling promotes inflammation, airway remodeling, and emphysema in chronic obstructive pulmonary disease
Z Lu, HP Van Eeckhoutte, G Liu, PM Nair… - American journal of …, 2021 - atsjournals.org
Rationale: Necroptosis, mediated by RIPK3 (receptor-interacting protein kinase 3) and
MLKL (mixed lineage kinase domain-like), is a form of regulated necrosis that can drive …
MLKL (mixed lineage kinase domain-like), is a form of regulated necrosis that can drive …
[HTML][HTML] A Glimpse of necroptosis and diseases
M Yang, W Chen, L He, D Liu, L Zhao… - Biomedicine & …, 2022 - Elsevier
Programmed cell death plays an important role in maintaining homeostasis. Necroptosis is a
type of programmed cell death that has been recently discovered. It is mediated by RIPK1 …
type of programmed cell death that has been recently discovered. It is mediated by RIPK1 …
Necroptosis in Pneumonia: Therapeutic Strategies and Future Perspectives
X Mei, Y Zhang, S Wang, H Wang, R Chen, K Ma… - Viruses, 2024 - mdpi.com
Pneumonia remains a major global health challenge, necessitating the development of
effective therapeutic approaches. Recently, necroptosis, a regulated form of cell death, has …
effective therapeutic approaches. Recently, necroptosis, a regulated form of cell death, has …
Collateral damage: necroptosis in the development of lung injury
H Faust, NS Mangalmurti - American Journal of Physiology …, 2020 - journals.physiology.org
Cell death is increasingly recognized as a driving factor in the development of acute lung
injury. Necroptosis, an immunogenic regulated cell death program important in innate …
injury. Necroptosis, an immunogenic regulated cell death program important in innate …
The role of necroptosis in cardiovascular disease
S Zhe-Wei, G Li-Sha, L Yue-Chun - Frontiers in pharmacology, 2018 - frontiersin.org
A newly discovered mechanism of cell death, programmed necrosis (necroptosis), combines
features of both necrosis and apoptosis. Necroptosis is tightly modulated by a series of …
features of both necrosis and apoptosis. Necroptosis is tightly modulated by a series of …