Enhanced bioavailability and pharmacokinetics parameters of Enalapril solid self nanoemulsifying oral dispersible tablet: Formulation, in vitro and in vivo evaluation

DH Hassan, AA Ammar, AA Ramadan… - Pharmaceutical …, 2023 - Taylor & Francis
Enalapril (EN) is an antihypertensive drug that is sparingly soluble in water with limited oral
bioavailability. Successfully prepared self-nanoemulsifying systems (SNES) loaded with EN …

Development, optimization, and characterization of solid self-nanoemulsifying drug delivery systems of valsartan using porous carriers

S Beg, S Swain, HP Singh, CN Patra, MEB Rao - Aaps Pharmscitech, 2012 - Springer
The present studies entail formulation development of novel solid self-nanoemulsifying drug
delivery systems (S-SNEDDS) of valsartan with improved oral bioavailability, and evaluation …

[PDF][PDF] Effect of oils, surfactants and cosurfactants on phase behavior and physicochemical properties of self-nanoemulsifying drug delivery system (SNEDDS) for …

A Nasr, A Gardouh, H Ghonaim, E Abdelghany… - Int J Appl …, 2016 - researchgate.net
Objective: The main purpose of this study was to optimize the different conditions for the
preparation of self-nanoemulsifying drug delivery system (SNEDDS) for both Irbesartan …

Formulation, characterization and in vivo evaluation of self-nanoemulsifying drug delivery system for oral delivery of valsartan

M Chopra, UY Nayak, A Kumar Gurram… - Current …, 2014 - ingentaconnect.com
Valsartan is an effective, highly selective and orally active antihypertensive exhibiting low
aqueous solubility and poor dissolution that limit its absorption resulting in low …

[PDF][PDF] Self-nanoemulsifying drug delivery systems of Valsartan: preparation and in-vitro characterization

PS Rajinikanth, NW Keat, S Garg - International journal of drug delivery, 2012 - core.ac.uk
The main objective this study is to prepare and evaluate the selfnanoemulsifying drug
delivery (SNEDDS) system in order to achieve a better dissolution rate of a poorly water …

Spontaneous emulsification of nifedipine-loaded self-nanoemulsifying drug delivery system

Y Weerapol, S Limmatvapirat… - AAPS …, 2015 - Springer
Self-nanoemulsifying drug delivery system (SNEDDS) can be used to improve dissolution of
poorly water-soluble drugs. The objective of this study was to prepare SNEDDS by using …

[HTML][HTML] Novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for oral delivery of olmesartan medoxomil: design, formulation, pharmacokinetic and …

A Nasr, A Gardouh, M Ghorab - Pharmaceutics, 2016 - mdpi.com
The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery
system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution …

Solid self-nanoemulsifying systems of olmesartan medoxomil: Formulation development, micromeritic characterization, in vitro and in vivo evaluation

S Beg, OP Katare, S Saini, B Garg, RK Khurana… - Powder technology, 2016 - Elsevier
The current studies entail development and evaluation of solid self-nanoemulsifying drug
delivery systems (S-SNEDDS) employing porous carriers for enhancing the oral …

Formulation of self-nanoemulsifying drug delivery system for telmisartan with improved dissolution and oral bioavailability

J Ahmad, K Kohli, SR Mir, S Amin - Journal of Dispersion Science …, 2011 - Taylor & Francis
To improve the dissolution and oral absorption of poorly water soluble drug-telmisartan, a
self-nanoemulsifying system (SNES) was developed, characterized, and its relative …

Formulation and in-vitro characterization of Self Nano-emulsifying Drug Delivery System (SNEDDS) for enhanced solubility of candesartan cilexetil

D Elsegaie, M Teaima, MI Tadrous… - Research Journal of …, 2019 - indianjournals.com
Candesartan cilexetil is the prodrug of candesartan, a selective angiotensin II receptor
antagonist, used in the management of hypertension and heart failure. It is characterized by …