Multikinase inhibitor treatment in thyroid cancer

OV Ancker, M Krüger, M Wehland, M Infanger… - International journal of …, 2019 - mdpi.com
Thyroid cancer is the most common endocrine malignancy. Most thyroid cancer types
respond well to conventional treatment consisting of surgery and radioactive iodine (RAI) …

Multikinase inhibitors: a new option for the treatment of thyroid cancer

ML Gild, M Bullock, BG Robinson… - Nature Reviews …, 2011 - nature.com
Thyroid cancer typically has a good outcome following standard treatments, which include
surgery, radioactive iodine ablation and treatment with TSH-suppressive levothyroxine …

Multikinase inhibitors in the treatment of thyroid cancer: specific role of lenvatinib

N Stjepanovic, J Capdevila - Biologics: Targets and Therapy, 2014 - Taylor & Francis
Thyroid cancers are the most frequent neoplasms of the endocrine system and in the initial
stages their prognosis is excellent. However, few therapeutic options are available for …

The adverse effect of hypertension in the treatment of thyroid cancer with multi-kinase inhibitors

OV Ancker, M Wehland, J Bauer, M Infanger… - International Journal of …, 2017 - mdpi.com
The treatment of thyroid cancer has promising prospects, mostly through the use of surgical
or radioactive iodine therapy. However, some thyroid cancers, such as progressive …

Multikinase inhibitors in thyroid cancer: timing of targeted therapy

ML Gild, VHM Tsang, RJ Clifton-Bligh… - Nature Reviews …, 2021 - nature.com
In the 9 years since the publication of our 2011 review of targeted treatment of thyroid cancer
with multikinase inhibitors, much has changed in the landscape of this heterogeneous …

Advances in thyroid cancer treatment: latest evidence and clinical potential

T Alonso-Gordoa, JJ Díez, M Durán… - … advances in medical …, 2015 - journals.sagepub.com
Advanced thyroid carcinoma is an infrequent tumor entity with limited treatment possibilities
until recently. The extraordinary improvement in the comprehension of genetic and …

Therapy of endocrine disease: response and toxicity of small-molecule tyrosine kinase inhibitors in patients with thyroid carcinoma: a systematic review and meta …

EN Klein Hesselink, D Steenvoorden… - European Journal of …, 2015 - academic.oup.com
Context Many tyrosine kinase inhibitors (TKIs) have been studied in patients with thyroid
carcinoma (TC). However, the effect and toxicity of various TKIs in differentiated TC (DTC) …

Thyroid cancers: from surgery to current and future systemic therapies through their molecular identities

L Lorusso, V Cappagli, L Valerio, C Giani… - International Journal of …, 2021 - mdpi.com
Differentiated thyroid cancers (DTC) are commonly and successfully treated with total
thyroidectomy plus/minus radioiodine therapy (RAI). Medullary thyroid cancer (MTC) is only …

Targeted therapies in advanced differentiated thyroid cancer

RM Carneiro, BA Carneiro, M Agulnik, PA Kopp… - Cancer treatment …, 2015 - Elsevier
Differentiated thyroid cancer is the most common endocrine malignancy, and its incidence
has been rising rapidly over the past 10 years. Although most patients with this disease have …

Lenvatinib for radioactive iodine-refractory differentiated thyroid carcinoma and candidate biomarkers associated with survival: a multicenter study in Korea

E Song, M Kim, EY Kim, BH Kim, DY Shin, HC Kang… - Thyroid, 2020 - liebertpub.com
Background: Lenvatinib, an oral multikinase inhibitor, is the latest addition to the treatment
options for radioactive iodine (RAI)-refractory progressive differentiated thyroid carcinoma …