For the treatment of malignancy, many therapeutic agents, including small molecules,
photosensitizers, immunomodulators, proteins and genes, and so forth, have been loaded …

A biodegradable micellar drug delivery system with a pH-responsive sheddable PEG shell
was developed using an acetal-linked poly (ethylene glycol)-block-polylactide (PEG-a-PLA) …

Polylactic acid (PLA) and its copolymers have a long history of safety in humans and an
extensive range of applications. PLA is biocompatible, biodegradable by hydrolysis and …

Abstract Poly (ethylene glycol)-block-poly (D, L-lactic acid)(PEG-b-PLA) micelles and poly
(D, L-lactic-co-glycolic acid)-block-polyethylene glycol)-block-poly (D, L-lactic-co-glycolic …

With the emergence of nanotechnology in drug delivery, colloidal systems and particularly
polymeric micelles have attracted great attention. Polymeric micelles formed by the self …

Current clinical and preclinical anticancer formulations are limited by their use of toxic
excipients and stability issues upon combining different drug formulations. We have found …

One of the renowned nanosized pharmaceutical carriers for delivery of poorly soluble drugs,
especially, in cancer, is micelles, which are self-assembled colloidal particles with a …

Poly (ethylene glycol)-poly (d, l-lactide) block copolymers (PEG-PLA) with varying
composition were prepared through successive ring-opening polymerization of ethylene …

Nanoparticles based on single-component synthetic polymers, such as poly (lactic acid-co-
glycolic acid)(PLGA), have been extensively studied for antitumor drug delivery and …

One constrain in the use of micellar carriers as drug delivery systems (DDSs) is their low
stability in aqueous solution. In this study “tree-shaped” copolymers of general formula …