Abstract Brain arteriolosclerosis (B-ASC), characterized by pathologic arteriolar wall
thickening, is a common finding at autopsy in aged persons and is associated with cognitive …

Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage,
and is the most common pathology underlying vascular cognitive impairment. Increasingly …

Alzheimer disease (AD) is the most common cause of dementia. Biological definitions of AD
are limited to the cerebral burden of amyloid β plaques, neurofibrillary pathology, and …

Cerebral amyloid angiopathy (CAA) is common in elderly individuals, especially those
affected with Alzheimer's disease. Eighteen brains with severe SCAA (SCAA) were …

Subcortical small-vessel disease (SSVD) is a disorder well characterized from the clinical,
imaging, and neuropathological viewpoints. SSVD is considered the most prevalent …

Hippocampal sclerosis of ageing is a prevalent brain disease that afflicts older persons and
has been linked with cerebrovascular pathology. Arteriolosclerosis is a subtype of …

The incidence and severity of cerebrovascular disease (CVD) increase with advancing age,
as does the risk of developing Alzheimer's disease (AD). Not surprisingly, heterogeneous …

The prevalence, morphology and pathogenesis of vascular dementia (VaD), recently termed
vascular cognitive impairment, are a matter of discussion, and currently used clinical …

Recent epidemiological and clinico-pathologic data suggest overlaps between Alzheimer
disease (AD) and cerebrovascular lesions that may magnify the effect of mild AD pathology …

Vascular dementia/vascular cognitive impairment (VaD/VCI) is not a single entity, but a large
group of conditions characterized by various clinical and morphological findings and …