Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells

E Spaeth, A Klopp, J Dembinski, M Andreeff, F Marini - Gene therapy, 2008 - nature.com
Mesenchymal stem cells (MSC) exhibit tropism for sites of tissue damage as well as the
tumor microenvironment. Many of the same inflammatory mediators that are secreted by …

The roles of mesenchymal stem cells in tumor inflammatory microenvironment

Z Sun, S Wang, RC Zhao - Journal of hematology & oncology, 2014 - Springer
Tumor behavior is not entirely determined by tumor cells. Studies have demonstrated that a
variety of non-tumor cells in the tumor microenvironment affect tumor behavior; thus, a new …

Tumor microenvironment: bone marrow-mesenchymal stem cells as key players

P Barcellos-de-Souza, V Gori, F Bambi… - Biochimica et Biophysica …, 2013 - Elsevier
Tumor progression is a multistep phenomenon in which tumor-associated stromal cells
perform an intricate cross-talk with tumor cells, supplying appropriate signals that may …

Mesenchymal stem cells in the tumor microenvironment

J Guan, JIE Chen - Biomedical reports, 2013 - spandidos-publications.com
Mesenchymal stem cells (MSCs) are non‑hematopoietic, multipotent cells, which are able to
differentiate to bone, adipose and cartilage tissue. MSCs have the characteristic of migration …

The role of MSCs in the tumor microenvironment and tumor progression

SY Ahn - Anticancer research, 2020 - ar.iiarjournals.org
Over the past few decades, longevity without disease has become an important topic
worldwide. However, as life expectancy increases, the number of patients with cancer is also …

Mesenchymal stem cells in the tumor microenvironment

H Atiya, L Frisbie, C Pressimone, L Coffman - … : Non-hematopoietic cells, 2020 - Springer
The interactions between tumor cells and the non-malignant stromal and immune cells that
make up the tumor microenvironment (TME) are critical to the pathophysiology of cancer …

[HTML][HTML] Mesenchymal stromal cells' role in tumor microenvironment: involvement of signaling pathways

AHN Kamdje, PT Kamga, RT Simo… - Cancer biology & …, 2017 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) are adult multipotent stem cells residing as pericytes in
various tissues and organs where they can differentiate into specialized cells to replace …

How to hit mesenchymal stromal cells and make the tumor microenvironment immunostimulant rather than immunosuppressive

A Poggi, S Varesano, MR Zocchi - Frontiers in immunology, 2018 - frontiersin.org
Experimental evidence indicates that mesenchymal stromal cells (MSCs) may regulate
tumor microenvironment (TME). It is conceivable that the interaction with MSC can influence …

Mesenchymal stem cell-mediated effects of tumor support or suppression

KJ Rhee, JI Lee, YW Eom - International journal of molecular sciences, 2015 - mdpi.com
Mesenchymal stem cells (MSCs) can exhibit a marked tropism towards site of tumors. Many
studies have reported that tumor progression and metastasis increase by MSCs. In contrast …

Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

Y Shi, L Du, L Lin, Y Wang - Nature reviews Drug discovery, 2017 - nature.com
Mesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), exist in many
tissues and are known to actively migrate to sites of tissue injury, where they participate in …