Concentrations of oocyte secreted GDF9 and BMP15 decrease with MII transition during human IVM

J Cadenas, SE Pors, A Kumar, B Kalra… - Reproductive Biology …, 2022 - Springer
Background The suggested effects of the oocyte secreted GDF9 and BMP15 growth factors
on oocyte maturation are currently based on recombinant proteins, and little is known about …

Increased GDF9 and BMP15 mRNA levels in cumulus granulosa cells correlate with oocyte maturation, fertilization, and embryo quality in humans

Y Li, RQ Li, SB Ou, NF Zhang, L Ren, LN Wei… - Reproductive biology …, 2014 - Springer
Abstract Background Oocyte secreted factors (OSFs), including growth differentiation factor 9
(GDF9) and bone morphogenetic protein 15 (BMP15), play an important role in the process …

Intrafollicular concentrations of the oocyte-secreted factors GDF9 and BMP15 vary inversely in polycystic ovaries

SG Kristensen, A Kumar, LS Mamsen… - The Journal of …, 2022 - academic.oup.com
Context The oocyte-secreted factors growth differentiation factor 9 (GDF9) and bone
morphogenetic protein 15 (BMP15) play essential roles in follicle development and oocyte …

[HTML][HTML] Application of specific ELISAs for BMP15 and GDF9 to cumulus cell extracts from infertile women

AE Krysta-Matter, AH Riepsamen, S Lien… - Molecular and Cellular …, 2023 - Elsevier
Abstract Bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9)
are oocyte-specific paracrine factors which regulate ovarian cumulus cell (CC) functions …

Age-related decline in the expression of GDF9 and BMP15 genes in follicle fluid and granulosa cells derived from poor ovarian responders

Y Gong, J Li-Ling, D Xiong, J Wei, T Zhong… - Journal of Ovarian …, 2021 - Springer
Background Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15
(BMP15) genes play important roles in folliculogenesis. Altered expression of the two have …

Effects of differing oocyte-secreted factors during mouse in vitro maturation on subsequent embryo and fetal development

J Sudiman, LJ Ritter, DK Feil, X Wang, K Chan… - Journal of assisted …, 2014 - Springer
Purpose We hypothesised that varying native oocyte-secreted factor (OSF) exposure or
using different recombinant OSF peptides would have differential effects on post-in vitro …

Oocyte bone morphogenetic protein 15, but not growth differentiation factor 9, is increased during gonadotropin-induced follicular development in the immature mouse …

X Guéripel, V Brun, A Gougeon - Biology of reproduction, 2006 - academic.oup.com
Bone morphogenetic protein (BMP) 15 and growth differentiation factor (GDF) 9 are oocyte-
secreted growth factors that are critical local regulators of ovarian function and may be …

Serum concentrations of oocyte-secreted factors BMP15 and GDF9 during IVF and in women with reproductive pathologies

AH Riepsamen, K Chan, S Lien, P Sweeten… - …, 2019 - academic.oup.com
Oocyte-secreted factors bone morphogenetic protein 15 (BMP15) and growth differentiation
factor 9 (GDF9) are critical for folliculogenesis and fertility. This study developed ELISAs for …

[HTML][HTML] Influence of follicular fluid GDF9 and BMP15 on embryo quality

F Gode, B Gulekli, E Dogan, P Korhan, S Dogan… - Fertility and sterility, 2011 - Elsevier
Objective To evaluate the association between follicular fluid levels of propeptide and
mature forms of growth differentiation factor (GDF) 9 and bone morphogenetic protein (BMP) …

Effects of Growth Differentiation Factor 9 and Bone Morphogenetic Protein 15 on the in vitro Maturation of Porcine Oocytes

ZL Lin, YH Li, YN Xu, QL Wang… - … in Domestic Animals, 2014 - Wiley Online Library
Contents Growth differentiation factor 9 (GDF 9) and bone morphogenetic protein 15 (BMP
15) are members of the transforming growth factor‐β (TGF‐β) family, and their roles in …