Genotypic HIV drug resistance testing is routinely used to guide clinical decisions. While
genotyping methods can be standardized, a slow, labor-intensive, and subjective manual …

The use of genotypic assays for determining drug resistance in human immunodeficiency
virus (HIV) type 1 (HIV-1)-infected patients is increasing. These tests lack standardization …

The ability of next-generation sequencing (NGS) technologies to detect low frequency HIV-1
drug resistance mutations (DRMs) not detected by dideoxynucleotide Sanger sequencing …

Interpreting the results of plasma human immunodeficiency virus type 1 (HIV-1) genotypic
drug-resistance tests is one of the most difficult tasks facing clinicians caring for HIV-1 …

HIV-1 genotyping has become a widely accepted tool for monitoring antiretroviral therapy.
However, the benefit of genotyping is limited by the need to interpret the mutation pattern in …

Identifying resistance to antiretroviral drugs is crucial for ensuring the successful treatment of
patients infected with viruses such as human immunodeficiency virus (HIV) or hepatitis C …

Drug resistance testing has proven its use to guide treatment decisions in HIV-1 infected
patients. Genotyping is the preferred technique for clinical drug resistance testing. Many …

Higher accessibility and decreasing costs of next generation sequencing (NGS), availability
of commercial kits, and development of dedicated analysis pipelines, have allowed an …

Next-generation sequencing (NGS) is increasingly used for HIV-1 drug resistance
genotyping. NGS methods have the potential for a more sensitive detection of low …

Highlights•Technological innovations enable the global roll-out of drug resistance
surveillance.•Next-generation sequencing provides an answer for simultaneous resistance …