Airway structure and function are key aspects of normal lung development, growth, and
aging, as well as of lung responses to the environment and the pathophysiology of important …

It is now established that airway smooth muscle (ASM) has roles in determining airway
structure and function, well beyond that as the major contractile element. Indeed, changes in …

Airway smooth muscle (ASM), an important tissue involved in the regulation of bronchomotor
tone, exists in the trachea and in the bronchial tree up to the terminal bronchioles. The …

Airway smooth muscle (ASM) plays a pivotal role in modulating bronchomotor tone but also
orchestrates and perpetuates airway inflammation and remodeling. Despite substantial …

The airway smooth muscle (ASM) plays an indispensable role in airway structure and
function. Dysfunction in ASM plays a central role in the pathogenesis of chronic obstructive …

Recent evidence points to progressive structural change in the airway wall, driven by
chronic local inflammation, as a fundamental component for development of irreversible …

Chronic asthma is an inflammatory airways disease characterized by pathological changes
in the airway smooth muscle (ASM) bundle that contribute to airway obstruction and …

Smooth muscle comprises a key functional component of both the airways and their
supporting vasculature. Dysfunction of smooth muscle contributes to and exacerbates a host …

Airway smooth muscle (ASM) is the main regulator of bronchomotor tone. Extensive studies
show that in addition to their physical property, human airway smooth muscle (ASM) cells …

The airway smooth muscle cell has a variety of properties, which confer on it the ability to
participate actively in the inflammatory process and the remodeling events, which …