Role of the innate immune system in the pathogenesis of multiple sclerosis

R Gandhi, A Laroni, HL Weiner - Journal of neuroimmunology, 2010 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease with heterogeneous
clinical presentations and course. MS is considered to be a T cell mediated disease but in …

The innate immune system in demyelinating disease

L Mayo, FJ Quintana, HL Weiner - Immunological reviews, 2012 - Wiley Online Library
Demyelinating diseases such as multiple sclerosis are chronic inflammatory autoimmune
diseases with a heterogeneous clinical presentation and course. Both the adaptive and the …

Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE

L Van Kaer, JL Postoak, C Wang, G Yang… - Cellular & molecular …, 2019 - nature.com
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) in which the immune system damages the protective insulation surrounding the nerve …

Insights into the immunopathogenesis of multiple sclerosis

N Hellings, J Raus, P Stinissen - Immunologic research, 2002 - Springer
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS). Significant progress has been made in our understanding of the etiology of MS. MS …

The contribution of immune and glial cell types in experimental autoimmune encephalomyelitis and multiple sclerosis

SS Duffy, JG Lees… - Multiple sclerosis …, 2014 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
characterised by widespread areas of focal demyelination. Its aetiology and pathogenesis …

[HTML][HTML] Multiple sclerosis and the role of immune cells

RA Høglund, AA Maghazachi - World journal of experimental …, 2014 - ncbi.nlm.nih.gov
Multiple sclerosis (MS) is a complex disease with many different immune cells involved in its
pathogenesis, and in particular T cells as the most recognized cell type. Recently, the innate …

The immune pathogenesis of multiple sclerosis

R Weissert - Journal of Neuroimmune Pharmacology, 2013 - Springer
Multiple sclerosis is an autoimmune disease of the central nervous system (CNS) that leads
to changes of nerve conduction due to damage of CNS–resident cells, primarily …

Update on inflammation, neurodegeneration, and immunoregulation in multiple sclerosis: therapeutic implications

JL Bennett, O Stüve - Clinical neuropharmacology, 2009 - journals.lww.com
Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease
of the central nervous system of uncertain etiology. There is consensus that a dysregulated …

Role of microglia in CNS autoimmunity

T Goldmann, M Prinz - Journal of Immunology Research, 2013 - Wiley Online Library
Multiple sclerosis (MS) is the most common autoimmune disease of the central nervous
system (CNS) in the Western world. The disease is characterized histologically by the …

The immune response in multiple sclerosis

S Rodríguez Murúa, MF Farez… - Annual Review of …, 2022 - annualreviews.org
Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative
disease that affects the central nervous system (CNS). MS is characterized by immune …